ArticleCommunications biology2021
Association between polygenic propensity for psychiatric disorders and nutrient intake.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed.
- Evidence for overlapping genetic architecture between lifestyle factors and severe mental disorders with different patterns across diagnoses.EBioMedicine · 2026Article
- Systematic Review and Meta-Analysis: Phenotypic Correlates of the Autism Polygenic Score.JAACAP open · 2025Article
- The genetic landscape of substance use disorders.Molecular psychiatry · 2024Review
- Review
- Attention-deficit/hyperactivity disorder.Nature reviews. Disease primers · 2024Review
- Do Poor Diet and Lifestyle Behaviors Modify the Genetic Susceptibility to Impulsivity in the General Population?Nutrients · 2023Article
- Association of Impulsivity With Food, Nutrients, and Fitness in a Longitudinal Birth Cohort Study.The international journal of neuropsychopharmacology · 2022Article
- En route to precision medicine for mental health: World Mental Health Day 2021.Communications biology · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Despite the observed associations between psychiatric disorders and nutrient intake, genetic studies are limited. We examined whether polygenic scores for psychiatric disorders are associated with nutrient intake in UK Biobank (N = 163,619) using linear mixed models. We found polygenic scores for attention-deficit/hyperactivity disorder, bipolar disorder, and schizophrenia showed the highest number of associations, while a polygenic score for autism spectrum disorder showed no association. The relatively weaker obsessive-compulsive disorder polygenic score showed the greatest effect sizes suggesting its association with diet traits may become more apparent with larger genome-wide analyses. A higher alcohol dependence polygenic score was associated with higher alcohol intake and individuals with higher persistent thinness polygenic scores reported their food to weigh less, both independent of socioeconomic status. Our findings suggest that polygenic propensity for a psychiatric disorder is associated with dietary behaviour. Note, nutrient intake was self-reported and findings must therefore be interpreted mindfully.
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Registered trials
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