ArticleScientific reports2021
Pan-transcriptome identifying master genes and regulation network in response to drought and salt stresses in Alfalfa (Medicago sativa L.).
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Genome-wide association study (GWAS) and transcriptome analysis reveal new candidate genes for leaf size in alfalfa.BMC plant biology · 2026Article
- Spatial Heterogeneity of Metabolic Response to Drought Stress inMetabolites · 2026Article
- Diversity of lncRNAs in the pan-transcriptome of maize inbred lines.BMC genomics · 2026Article
- Genomic resources for Australian alfalfa (Medicago sativa L.) genomics: reformatted reference genome, annotated variants, gene presence-absence and diversity analysis from genome re-sequencing.BMC plant biology · 2025Article
- Identification of the Plant Defensin (MsPDF) Gene Family inPlants (Basel, Switzerland) · 2025Article
- Genome-Wide Association and Genomic Prediction of Alfalfa (International journal of molecular sciences · 2025Article
- Thriving in a salty future: morpho-anatomical, physiological and molecular adaptations to salt stress in alfalfa (Medicago sativa L.) and other crops.Annals of botany · 2024Review
- Genome-Wide Identification and Expression Analysis of the Alfalfa (International journal of molecular sciences · 2024Article
- Differential gene expression of salt-tolerant alfalfa in response to salinity and inoculation by Ensifer meliloti.BMC plant biology · 2024Article
- Long Noncoding RNAs in Response to Hyperosmolarity Stress, but Not Salt Stress, Were Mainly Enriched in the Rice Roots.International journal of molecular sciences · 2024Article
- Whole-Transcriptome Sequencing Reveals the Global Molecular Responses and NAC Transcription Factors Involved in Drought Stress inAntioxidants (Basel, Switzerland) · 2024Article
- Multi-trait modeling and machine learning discover new markers associated with stem traits in alfalfa.Frontiers in plant science · 2024Article
- Genetic Mapping of Tolerance to Bacterial Stem Blight Caused byPlants (Basel, Switzerland) · 2023Article
- Novel Tri-Segmented Rhabdoviruses: A Data Mining Expedition Unveils the Cryptic Diversity of Cytorhabdoviruses.Viruses · 2023Article
- Long read sequencing to reveal the full complexity of a plant transcriptome by targeting both standard and long workflows.Plant methods · 2023Article
- Elucidation of Physiological, Transcriptomic and Metabolomic Salinity Response Mechanisms inPlants (Basel, Switzerland) · 2023Article
- Identification of genetic loci associated with five agronomic traits in alfalfa using multi-environment trials.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Identification, biogenesis, function, and mechanism of action of circular RNAs in plants.Plant communications · 2023Review
- A Pan-Transcriptome Analysis Indicates Efficient Downregulation of the FIB Genes Plays a Critical Role in the Response of Alfalfa to Cold Stress.Plants (Basel, Switzerland) · 2022Article
- Legume Pangenome: Status and Scope for Crop Improvement.Plants (Basel, Switzerland) · 2022Review
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3 authors.
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Abstract
Alfalfa is an important legume forage grown worldwide and its productivity is affected by environmental stresses such as drought and high salinity. In this work, three alfalfa germplasms with contrasting tolerances to drought and high salinity were used for unraveling the transcriptomic responses to drought and salt stresses. Twenty-one different RNA samples from different germplasm, stress conditions or tissue sources (leaf, stem and root) were extracted and sequenced using the PacBio (Iso-Seq) and the Illumina platforms to obtain full-length transcriptomic profiles. A total of 1,124,275 and 91,378 unique isoforms and genes were obtained, respectively. Comparative analysis of transcriptomes identified differentially expressed genes and isoforms as well as transcriptional and post-transcriptional modifications such as alternative splicing events, fusion genes and nonsense-mediated mRNA decay events and non-coding RNA such as circRNA and lncRNA. This is the first time to identify the diversity of circRNA and lncRNA in response to drought and high salinity in alfalfa. The analysis of weighted gene co-expression network allowed to identify master genes and isoforms that may play important roles on drought and salt stress tolerance in alfalfa. This work provides insight for understanding the mechanisms by which drought and salt stresses affect alfalfa growth at the whole genome level.
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