Evidence map›Paper›PMID 34446754›Full record

ArticleScientific reports2021

Phytochemistry reflects different evolutionary history in traditional classes versus specialized structural motifs.

Kathryn A Uckele, Joshua P Jahner, Eric J Tepe, Lora A Richards, Lee A Dyer, Kaitlin M Ochsenrider, Casey S Philbin, Massuo J Kato, Lydia F Yamaguchi, Matthew L Forister and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Structural innovation and flexibility in plant chemical defenses.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Structural innovation in the evolution of plant chemical defense.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Pharmacokinetic Profile of Extracts from the Chayote (Molecules (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Molecules (Basel, Switzerland) · 2025
    Article
  6. Exploration of the distribution and host range ofBiodiversity data journal · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Kathryn A Uckele *Program in Ecology, Evolution, and Conservation Biology, University of Nevada, Reno, NV, 89557, USA.
Joshua P Jahner *Program in Ecology, Evolution, and Conservation Biology, University of Nevada, Reno, NV, 89557, USA. jpjahner@gmail.com.
Eric J TepeDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH, 45221, USA.
Lora A RichardsProgram in Ecology, Evolution, and Conservation Biology, University of Nevada, Reno, NV, 89557, USA.
Lee A DyerProgram in Ecology, Evolution, and Conservation Biology, University of Nevada, Reno, NV, 89557, USA.
Kaitlin M OchsenriderDepartment of Chemistry, University of Nevada, Reno, NV, 89557, USA.
Casey S PhilbinHitchcock Center for Chemical Ecology, University of Nevada, Reno, NV, 89557, USA.
Massuo J KatoDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil.
Lydia F YamaguchiDepartment of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, São Paulo, Brazil.
Matthew L ForisterProgram in Ecology, Evolution, and Conservation Biology, University of Nevada, Reno, NV, 89557, USA.
Angela M SmilanichProgram in Ecology, Evolution, and Conservation Biology, University of Nevada, Reno, NV, 89557, USA.
Craig D DodsonDepartment of Chemistry, University of Nevada, Reno, NV, 89557, USA.
Christopher S JeffreyProgram in Ecology, Evolution, and Conservation Biology, University of Nevada, Reno, NV, 89557, USA.
Thomas L ParchmanProgram in Ecology, Evolution, and Conservation Biology, University of Nevada, Reno, NV, 89557, USA.
University of Nevada, Reno · USUniversidade de São Paulo · BRInstituto Nacional de Biodiversidad · ECUniversity of Cincinnati · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foundational hypotheses addressing plant-insect codiversification and plant defense theory typically assume a macroevolutionary pattern whereby closely related plants have similar chemical profiles. However, numerous studies have documented variation in the degree of phytochemical trait lability, raising the possibility that phytochemical evolution is more nuanced than initially assumed. We utilize proton nuclear magnetic resonance (

Identifiers

PMID34446754
PMCPMC8390663
OpenAlexW3193287628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.