Evidence map›Paper›PMID 34446582›Full record

ReviewScience (New York, N.Y.)2021

Airborne transmission of respiratory viruses.

Chia C Wang, Kimberly A Prather, Josué Sznitman, Jose L Jimenez, Seema S Lakdawala, Zeynep Tufekci, Linsey C Marr

Abstract readReview
In one paragraph

Review in Science (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 557 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
557citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

557 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Mpox Airborne Transmission: A Systematic Review.Reviews in medical virology · 2026
    Pooled it
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  4. Global meta-analysis of short-term associations between ambient temperature and pathogen-specific respiratory infections, 2004 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Pooled it
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  18. Influenza.Nature reviews. Disease primers · 2026
    Review
  19. Article
  20. Review

497 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Chia C WangDepartment of Chemistry, National Sun Yat-sen University, Kaohsiung, Taiwan 804, Republic of China. chiawang@mail.nsysu.edu.tw kprather@ucsd.edu.ORCID 0000-0003-3214-9937
Kimberly A PratherScripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92037, USA. chiawang@mail.nsysu.edu.tw kprather@ucsd.edu.ORCID 0000-0003-3048-9890
Josué SznitmanDepartment of Biomedical Engineering, Israel Institute of Technology, Haifa 32000, Israel.ORCID 0000-0001-8217-3842
Jose L JimenezDepartment of Biomedical Engineering, Israel Institute of Technology, Haifa 32000, Israel.ORCID 0000-0001-6203-1847
Seema S LakdawalaDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.ORCID 0000-0002-7679-2150
Zeynep TufekciSchool of Information and Department of Sociology, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0002-7806-0025
Linsey C MarrAerosol Science Research Center, National Sun Yat-sen University, Kaohsiung, Taiwan 804, Republic of China.ORCID 0000-0003-3628-6891

Funding

NIAID NIH HHS HHSN272201400007C
6 · The paper itself

Abstract

The COVID-19 pandemic has revealed critical knowledge gaps in our understanding of and a need to update the traditional view of transmission pathways for respiratory viruses. The long-standing definitions of droplet and airborne transmission do not account for the mechanisms by which virus-laden respiratory droplets and aerosols travel through the air and lead to infection. In this Review, we discuss current evidence regarding the transmission of respiratory viruses by aerosols-how they are generated, transported, and deposited, as well as the factors affecting the relative contributions of droplet-spray deposition versus aerosol inhalation as modes of transmission. Improved understanding of aerosol transmission brought about by studies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection requires a reevaluation of the major transmission pathways for other respiratory viruses, which will allow better-informed controls to reduce airborne transmission.

Indexed as

Air MicrobiologySARS-CoV-2Virus Physiological PhenomenaAerosolsCOVID-19Disease Transmission, InfectiousHumansMicrobial ViabilityParticle SizeRespiratory SystemRespiratory Tract InfectionsViral LoadVirus DiseasesVirusesAerosols

Identifiers

PMID34446582
PMCPMC8721651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.