Evidence map›Paper›PMID 34446511›Full record

ArticleBMJ case reports2021

Aseptic meningitis and hydrocephalus secondary to neurosarcoidosis.

Anmol Pandey, Thomas Stoker, Lukasz A Adamczyk, Sybil Stacpoole

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Anmol PandeyDepartment of Neurology, The National Hospital for Neurology and Neurosurgery, UCL Queen Square Institute of Neurology, University College London Hospitals NHS Foundation Trust, London, UK anmol.pandey@nhs.net.
Thomas StokerDepartment of Neurology, The National Hospital for Neurology and Neurosurgery, UCL Queen Square Institute of Neurology, University College London Hospitals NHS Foundation Trust, London, UK.
Lukasz A AdamczykDepartment of Histopathology, Peterborough City Hospital, North West Anglia NHS Foundation Trust, Peterborough, UK.
Sybil StacpooleDepartment of Neurology, Peterborough City Hospital, North West Anglia NHS Foundation Trust, Peterborough, UK.
Peterborough City Hospital · GBUniversity College London · GBUniversity College London Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 53-year-old woman presented to hospital with gait instability, urinary incontinence and confusion. She had a 4-month history of headache, blurred vision, personality change and memory problems. Magnetic Resonance Imaging of the brain after contrast application showed tectal plate and occipital enhancement, as well as a known hydrocephalus. Cerebrospinal fluid showed aseptic meningitis with no evidence of clonal expansion. After further imaging that showed generalised lymphadenopathy and subsequent tissue biopsy that showed granulomatous lymphadenitis, she was diagnosed with neurosarcoidosis. She was treated with steroids which resulted in immediate cognitive and motor improvements as well as resolution of her urinary incontinence. We discuss the features of this case that pointed towards neoplastic, infective and other autoimmune aetiologies. We describe how they were excluded and provide the rationale for our treatment. This case demonstrates an important sequela sarcoidosis, and we conclude by recommending a multidisciplinary approach towards its diagnosis and management.

Indexed as

Central Nervous System DiseasesHydrocephalusMeningitis, AsepticSarcoidosisFemaleHumansMagnetic Resonance ImagingMiddle Agedheadache (including migraines)hydrocephalusmemory disordersneuroimagingneurology (drugs and medicines)

Identifiers

PMID34446511
PMCPMC8395265
OpenAlexW3193297657

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.