ArticleBMJ case reports2021
Large anastomotic leak: endoscopic treatment using combined fibrin glue and polyglycolic acid (PGA) sheets.
Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Treatment of colorectal leaks with the VACStent-Colon: results of the VACStent feasibility trial.Surgical endoscopy · 2026Article
- Rendezvous Stenting Technique for Anastomotic Leak After Total Gastrectomy: A Feasibility Study.Medicina (Kaunas, Lithuania) · 2026Article
- Polyglycolic acid-cyanoacrylate complex for prevention of major intestinal anastomotic leakage in a rat model: an experimental animal study.Annals of surgical treatment and research · 2025Article
- Physical pressure resistance of gastrointestinal anastomotic site via plate of polyglycolic acid promoting fibrosis.Scientific reports · 2024Article
- Endoscopic treatment of anastomotic leakage after colorectal surgery by using polyglycolic acid sheets and fibrin glue.DEN open · 2024Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anastomotic leak after gastrectomy is a major complication and various endoscopic methods have been suggested. However, the treatment of large-sized leaks remains a challenge. Here, we present a case of a large anastomotic leak successfully treated endoscopically using a combination of fibrin glue and polyglycolic acid (PGA) sheets. A 68-year-old man who underwent laparoscopic total gastrectomy and oesophagojejunal anastomosis presented with abdominal pain and fever. In the endoscopic examination, two fistulas were observed at the anastomosis site. One was small (0.6 cm) while the other measured 2.5 cm. For the large leak, endoscopic treatment using endoclip and detachable snare was attempted, but failed. Subsequently, fibrin glue was injected into the large fistula through an endoscope. After 28 days, the size of the fistula was reduced and PGA sheets were inserted into the remaining fistula. After about 4 weeks, leaks were observed to be completely healed.
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