Evidence map›Paper›PMID 34446476›Full record

Observational studyBMJ open2021

Umbilical artery lactate levels and associated maternal and newborn characteristics at Mulago National Referral Hospital: a cross-sectional observational study.

Victor Ogik, Mark Muyingo, Moses Musooko, Jolly Nankunda

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05468515 (Reference Interval for Pulse Oxygen Saturation in Neonates at High Altitudes During First 2 Hours and Umbilical Artery Blood Gas), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05468515 completednot on this mapstarted 2022, after this paper: background citation

Reference Interval for Pulse Oxygen Saturation in Neonates at High Altitudes During First 2 Hours and Umbilical Artery Blood Gas: a Multicenter Prospective Study

TypeobservationalSponsorChildren's Hospital of Fudan UniversityRan2022 to 2023Enrolled956ConditionsNeonatal Disease, Altitude HypoxiaArmspulse oxygen saturation
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Victor OgikDepartment of Obstetrics and Gynecology, Makerere University College of Health Sciences, Kampala, Uganda victorkogik@gmail.com.ORCID 0000-0002-7584-5097
Mark MuyingoDepartment of Obstetrics and Gynecology, Makerere University College of Health Sciences, Kampala, Uganda.
Moses MusookoDepartment of Obstetrics and Gynecology, Mulago National Referral Hospital, Kampala, Uganda.
Jolly NankundaDepartment of Pediatrics-Neonatology, Mulago National Referral Hospital, Kampala, Uganda.
Makerere University · UGMulago Hospital · UG

Funding

Health Professions Education and training for strengthening the health system and services in UgandaR25TW011213 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KIGULI, SARAH · 2018 to 2022
$3.4M
FIC NIH HHS R25 TW011213
6 · The paper itself

Abstract

objectiveTo determine the maternal and newborn characteristics associated with high umbilical artery lactate levels at Mulago National Referral Hospital.

designCross-sectional observational study.

settingDepartment of Obstetrics and Gynecology at a national referral hospital located in the capital of Uganda, Kampala.

participantsWe randomly selected 720 pregnant mothers at term who presented in labour and their newborn babies. PRIMARY OUTCOME: Umbilical artery lactate level.

resultsDuring the study, there were 579 vaginal deliveries (18 instrumental) and 141 caesarean sections which met the inclusion criteria. One hundred and eighty-seven neonates (187) had high arterial lactate levels. The following factors were associated with an increased likelihood of high lactate concentration: male sex (adjusted OR (aOR)=1.71; 95% CI 1.16 to 2.54; p

conclusionAbout a fifth of the babies born in Mulago National Referral Hospital during the study period had high umbilical artery lactate. The maternal-fetal factors significantly associated with high umbilical artery lactate levels included: baby's sex, mother's gravidity, meconium-stained amniotic fluid and oxytocin administration during labour.

Indexed as

Referral and ConsultationUmbilical ArteriesCross-Sectional StudiesFemaleHospitalsHumansInfant, NewbornLactatesMalePregnancyUgandaLactatesfetal medicinematernal medicineneonatology

Identifiers

PMID34446476
PMCPMC8395270
OpenAlexW3195438158

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.