Evidence map›Paper›PMID 34446471›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2021

Quality Diet Index and Risk of Pancreatic Cancer: Findings from the Singapore Chinese Health Study.

Hung N Luu, Pedram Paragomi, Aizhen Jin, Renwei Wang, Nithya Neelakantan, Rob M van Dam, Randall E Brand, Woon-Puay Koh, Jian-Min Yuan

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Adherence to Mediterranean Diet and Risk of Pancreatic Cancer: Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023
    Pooled it
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Diet Quality and Pancreatic Cancer Incidence in the Multiethnic Cohort.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Hung N LuuUPMC Hillman Cancer Center, Pittsburgh, Pennsylvania. luuh@upmc.edu hnl11@pitt.edu.ORCID 0000-0002-2172-1849
Pedram ParagomiUPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.ORCID 0000-0002-5471-4979
Aizhen JinYong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore.
Renwei WangUPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.
Nithya NeelakantanSaw Swee Hock School of Public Health, National University of Singapore, Singapore.
Rob M van DamSaw Swee Hock School of Public Health, National University of Singapore, Singapore.ORCID 0000-0002-7354-8734
Randall E BrandUPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.ORCID 0000-0002-4136-3313
Woon-Puay KohYong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore.ORCID 0000-0002-5674-6341
Jian-Min YuanUPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.ORCID 0000-0002-4620-3108
University of Pittsburgh · USNational University of Singapore · SGUPMC Hillman Cancer Center · USAgency for Science, Technology and Research · SGNational University Health System · SG

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
Prospective studies of cancer etiology and prevention in Shanghai and SingaporeR01CA144034 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2010 to 2014
$7.0M
Cancer epidemiology cohorts in Shanghai and Singapore UM1CA182876 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2014 to 2018
$4.3M
Translational Research Training in Cancer Prevention and ControlT32CA186873 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Kathryn H. Schmitz, Jian-Min Yuan · 2014 to 2026
$2.7M
The Singapore Chinese Health StudyU01CA182876 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2019 to 2019
$150k
NCI NIH HHS P30 CA047904NCI NIH HHS R01 CA144034NCI NIH HHS T32 CA186873NCI NIH HHS U01 CA182876NCI NIH HHS UM1 CA182876
6 · The paper itself

Abstract

backgroundLimited research has been conducted on the effect of quality diet index (QDI), which represents a comprehensive assessment of healthy diet quality and quantity, on pancreatic cancer risk in Asian populations.

methodsUsing data from the Singapore Chinese Health Study, a prospective cohort of 63,257 middle-aged or older Chinese men and women, four QDI scores: the Alternative Health Eating Index-2010 (AHEI-2010), the alternate Mediterranean Diet (aMED), the Dietary Approaches to Stop Hypertension (DASH), and the Heathy Diet Indicator (HDI), at baseline were calculated. After 25 years of follow-up, 311 cohort participants developed pancreatic cancer. Cox proportional hazard regression method was used to estimate HR and 95% confidence interval (CI) for pancreatic cancer associated with higher QDI scores.

resultsHigher scores of AHEI-2010, aMED, and DASH were significantly associated with lower pancreatic cancer risk (all

conclusionsHigher QDI scores were significantly associated with reduced risk of pancreatic cancer. IMPACT: The consistent results across multiple QDIs shows that adherence to a healthy diet may lower pancreatic cancer risk, suggesting that dietary modification may be a promising approach for primary prevention of pancreatic cancer.

Indexed as

Diet, HealthyAgedAged, 80 and overAsian PeopleDiet SurveysFemaleHumansMaleMiddle AgedPancreatic NeoplasmsProspective StudiesRisk AssessmentSingapore

Identifiers

PMID34446471
PMCPMC8568638
OpenAlexW3195120959

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.