Evidence map›Paper›PMID 34446458›Full record

ArticleAJNR. American journal of neuroradiology2021

The Brain Metabolic Signature in Superagers Using In Vivo

L L de Godoy, A Studart-Neto, M Wylezinska-Arridge, M H Tsunemi, N C Moraes, M S Yassuda, A M Coutinho, C A Buchpiguel, R Nitrini, S Bisdas and 1 more

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Phenotyping Superagers Using Resting-State fMRI.AJNR. American journal of neuroradiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

L L de GodoyFrom the Department of Radiology and Oncology (L.L.d.G., C.d.C.L.), Hospital das Clínicas, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0001-5956-5741
A Studart-NetoDepartment of Neurology (A.S.-N., N.C.M., M.S.Y., R.N.), Hospital das Clínicas, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0003-2260-5986
M Wylezinska-ArridgeThe National Hospital of Neurology and Neurosurgery (M.W.-A., S.B.), University College London, London, UK.ORCID 0000-0002-2361-1029
M H TsunemiDepartment of Biostatistics, Institute of Biosciences (M.H.T.), Universidade Estadual Paulista, Botucatu, Sao Paulo, SP, Brazil.ORCID 0000-0002-9585-4230
N C MoraesDepartment of Neurology (A.S.-N., N.C.M., M.S.Y., R.N.), Hospital das Clínicas, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0002-8439-6828
M S YassudaDepartment of Neurology (A.S.-N., N.C.M., M.S.Y., R.N.), Hospital das Clínicas, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0002-9182-2450
A M CoutinhoDivision and Laboratory of Nuclear Medicine (A.M.C., C.A.B.), Department of Radiology and Oncology, Hospital das Clínicas, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0002-5555-4583
C A BuchpiguelDivision and Laboratory of Nuclear Medicine (A.M.C., C.A.B.), Department of Radiology and Oncology, Hospital das Clínicas, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0003-0956-2790
R NitriniDepartment of Neurology (A.S.-N., N.C.M., M.S.Y., R.N.), Hospital das Clínicas, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0002-5721-1525
S BisdasThe National Hospital of Neurology and Neurosurgery (M.W.-A., S.B.), University College London, London, UK.ORCID 0000-0001-9930-5549
C da Costa LeiteFrom the Department of Radiology and Oncology (L.L.d.G., C.d.C.L.), Hospital das Clínicas, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID 0000-0002-1168-0780

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeYouthful memory performance in older adults may reflect an underlying resilience to the conventional pathways of aging. Subjects having this unusual characteristic have been recently termed "superagers." This study aimed to explore the significance of imaging biomarkers acquired by MATERIALS AND

methodsFifty-five patients older than 80 years of age were screened using a detailed neuropsychological protocol, and 25 participants, comprising 12 superagers and 13 age-matched controls, were statistically analyzed. We used state-of-the-art 3T

resultsThe main finding observed was a higher total

conclusions

Indexed as

BrainBrain MappingAgedCognitionHumansPilot ProjectsProton Magnetic Resonance Spectroscopy

Identifiers

PMID34446458
PMCPMC8562753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.