Evidence map›Paper›PMID 34446110›Full record

ArticleImplementation science communications2021

The CircumVent Project: a CPAP/O

Aimalohi A Ahonkhai, Adesola Z Musa, André A Fenton, Muktar H Aliyu, Igho Ofotokun, Alex Hornstein, Baba M Musa, Nnamdi Nwosu, Ifeoma Ulasi, Samuel Ajayi and 11 more

Registry-linked trialAbstract read
In one paragraph

Article in Implementation science communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04929691 (The CircumVent Project), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04929691 naunknown statusnot on this map

The CircumVent Project: A CPAP/O2 Helmet Solution for Non-Invasive Ventilation Using an Implementation Research Framework

TypeinterventionalSponsorNew York UniversityRan2020 to 2021Enrolled370ConditionsSARS-CoV-2 Acute Respiratory Disease, COVID-19 Respiratory InfectionArmsCPAP helmet, Standard of care non-helmet based CPAP ventilation
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Oxygen as an Essential Medicine.Critical care clinics · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Aimalohi A AhonkhaiVanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Adesola Z MusaNigerian Institute of Medical Research, Lagos, Nigeria.
André A FentonCenter for Neural Science and Neuroscience Institute, NYU Langone Medical Center, New York, USA. af95@nyu.edu.
Muktar H AliyuVanderbilt Institute for Global Health, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID http://orcid.org/0000-0001-9504-4679
Igho OfotokunEmory University, Atlanta, GA, USA.
Alex HornsteinVentilator Project, LLC, Boston, USA.
Baba M MusaAminu Kano Teaching Hospital, Kano, Nigeria.
Nnamdi NwosuUniversity of Nigeria Teaching Hospital, Enugu, Nigeria.
Ifeoma UlasiUniversity of Nigeria Teaching Hospital, Enugu, Nigeria.
Samuel AjayiUniversity College Hospital, Ibadan, Nigeria.
Catherine FaladeUniversity College Hospital, Ibadan, Nigeria.
Adedamola DadaFederal Medical Centre, Ebute Metta, Lagos, Nigeria.
Aliyu AbduAminu Kano Teaching Hospital, Kano, Nigeria.
Mogaji SundayFederal Medical Centre, Ebute Metta, Lagos, Nigeria.
Adenike OdewabiLagos University Teaching Hospital, Lagos, Nigeria.
Muyiwa K RotimiFederal Medical Centre, Abeokuta, Nigeria.
Onome OguehDelta State University Teaching Hospital, Oghara, Nigeria.
Alan SteinbachJefferson Health-Jefferson Torresdale Hospital, Philadelphia, USA.
Gbenga OgedegbeCenter for Neural Science and Neuroscience Institute, NYU Langone Medical Center, New York, USA.
Babatunde L SalakoNigerian Institute of Medical Research, Lagos, Nigeria.
Oliver C EzechiNigerian Institute of Medical Research, Lagos, Nigeria.

Funding

aliko dangote foundation GS 2008-0001cdc foundation Award number 1085.1
6 · The paper itself

Abstract

backgroundAcute respiratory failure, a major cause of death in COVID-19, is managed with high-flow oxygen therapy via invasive mechanical ventilation. In resource-limited settings like Nigeria, the shortage of ventilators and oxygen supply makes this option challenging. Evidence-based non-invasive alternatives to mechanical ventilation such as the use of continuous positive airway pressure (CPAP) devices exist, but there have been concerns that non-invasive ventilation may expose healthcare workers to infection from aerosolized dispersion of SARS-CoV-2. We propose to evaluate the feasibility, adaptability and acceptability of a CPAP/O

methodsThe study will occur in 4 stages: (1) convene a Steering Committee of key stakeholders and recruit implementation sites; (2) use the integrated Promoting Action on Research Implementation in Health Services (i-PARiHS) framework to guide a needs assessment of treatment centers' capacity to use high-flow oxygen therapy to treat COVID-19 patients and utilize the findings to develop an implementation strategy for the use of a CPAP/O DISCUSSION: The CPAP/O

trial registrationNCT04929691. Registered June 18, 2021-retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT04929691.

Indexed as

Implementation scienceNigeriaNon-invasive ventilationSARS-CoV-2, COVID-19 infection

Identifiers

PMID34446110
PMCPMC8390034

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.