Evidence map›Paper›PMID 34445768›Full record

ReviewInternational journal of molecular sciences2021

Negative Influence by the Force: Mechanically Induced Hyperpolarization via K

Miklós Lengyel, Péter Enyedi, Gábor Czirják

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Mechanosensitive receptors in migraine: a systematic review.The journal of headache and pain · 2024
    Pooled it
  2. Review
  3. Lipid Regulation of Mechanosensitive Ion Channels.International journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. KPflugers Archiv : European journal of physiology · 2025
    Article
  9. Cannabinoid inhibition of mechanosensitive KbioRxiv : the preprint server for biology · 2024
    Article
  10. Review
  11. The mechanosensitive ion channel Piezo1 contributes to ultrasound neuromodulation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Miklós LengyelDepartment of Physiology, Semmelweis University, P.O. Box 2, H-1428 Budapest, Hungary.ORCID 0000-0001-6382-6369
Péter EnyediDepartment of Physiology, Semmelweis University, P.O. Box 2, H-1428 Budapest, Hungary.
Gábor CzirjákDepartment of Physiology, Semmelweis University, P.O. Box 2, H-1428 Budapest, Hungary.ORCID 0000-0002-5485-2327
Semmelweis University · HU

Funding

Hungarian Scientific Research Fund NKFIH K-127988
6 · The paper itself

Abstract

The two-pore domain K

Indexed as

AnimalsCell MembraneHumansLipid BilayersMembrane PotentialsPhysical PhenomenaPotassium Channels, Tandem Pore DomainLipid BilayersPotassium Channels, Tandem Pore DomainKCNK10KCNK2KCNK4mechanosensitivemembrane tensionpotassium channelstretchTREK1TREK2

Identifiers

PMID34445768
PMCPMC8396510
OpenAlexW3195320991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.