ReviewInternational journal of molecular sciences2021
Arteriovenous Malformations-Current Understanding of the Pathogenesis with Implications for Treatment.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Role of thalidomide in angiodysplasia-related gastrointestinal bleeding: a systematic review.Frontiers in gastroenterology (Lausanne, Switzerland) · 2026Pooled it
- Effectiveness and safety of embolization for basal ganglia or thalamic arteriovenous malformations: a systematic review and meta-analysis.Neuroradiology · 2025Pooled it
- Multiple arteriovenous malformations due to liver failure: An unusual etiology.Journal of vascular surgery cases and innovative techniques · 2026Article
- Targeting stiffness-dependent YAP/TAZ restores angiogenesis dynamics impaired by ALK1 knockout in silico.PLoS computational biology · 2026Article
- An unusual superior mesenteric arteriovenous malformation causing obscure gastrointestinal bleeding: a case report.BMC gastroenterology · 2026Article
- Congenital arteriovenous malformation of the thoracic aorta treated with thoracic endovascular aortic repair (TEVAR).Journal of vascular surgery cases and innovative techniques · 2026Article
- Complex Management of High-Flow Gastrointestinal Arteriovenous Malformation With Chronic Portomesenteric Thrombosis in PTEN Hamartoma Tumor Syndrome.ACG case reports journal · 2026Article
- Functional and Hemodynamic Restoration After Microsurgical Resection of Compact High-Flow Temporo-Parieto-Occipital Arteriovenous Malformation.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Arteriovenous Malformations (AVMs): Molecular Pathogenesis, Clinical Features, and Emerging Therapeutic Strategies.Biomolecules · 2025Review
- Forehead Arteriovenous Malformation Embolization Complicated by Glue Migration into the Cavernous Sinus: A Case Report of a Rare Complication.Archives of plastic surgery · 2025Article
- Fatal rupture of a flow-related Iliac artery aneurysm associated with an enormous arteriovenous malformation of abdominal wall and left thigh.BMC cardiovascular disorders · 2025Article
- Uterine Arteriovenous Malformation Presenting with Amenorrhea-A Rare Case Report and Literature Review.Reports (MDPI) · 2025Article
- Spinal arteriovenous malformation associated with congenital dermal sinus: a case report.Journal of medical case reports · 2025Article
- Endovascular Management of a Giant Renal Artery Aneurysm With Arteriovenous Malformation: A Case Report.Cureus · 2025Article
- Endovascular Treatment of Extracranial Arteriovenous Malformations: A Retrospective Monocentric Case-Series Study.Tomography (Ann Arbor, Mich.) · 2025Article
- Use of dermatologic ultrasound for diagnosis and surgical planning of a cutaneous arteriovenous malformation of the supratrochlear artery: A case report.JAAD case reports · 2025Article
- Monocyte-Derived cxcl12 Guides a Directional Migration of Blood Vessels in Zebrafish.Arteriosclerosis, thrombosis, and vascular biology · 2025Article
- Spetzler-Martin grade I and II cerebral arteriovenous malformations: a propensity-score matched analysis of resection and stereotactic radiosurgery in adult patients.Neurosurgical review · 2025Article
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Arteriovenous malformations are a vascular anomaly typically present at birth, characterized by an abnormal connection between an artery and a vein (bypassing the capillaries). These high flow lesions can vary in size and location. Therapeutic approaches are limited, and AVMs can cause significant morbidity and mortality. Here, we describe our current understanding of the pathogenesis of arteriovenous malformations based on preclinical and clinical findings. We discuss past and present accomplishments and challenges in the field and identify research gaps that need to be filled for the successful development of therapeutic strategies in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.