Evidence map›Paper›PMID 34445634›Full record

ArticleInternational journal of molecular sciences2021

Identification of the Ghrelin and Cannabinoid CB

Jaume Lillo, Alejandro Lillo, David A Zafra, Cristina Miralpeix, Rafael Rivas-Santisteban, Núria Casals, Gemma Navarro, Rafael Franco

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jaume LilloCentro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CiberNed), National Institute of Health Carlos III, Valderrebollo, 5, 28031 Madrid, Spain.
Alejandro LilloDepartment of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona, 08028 Barcelona, Spain.
David A ZafraDepartment of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona, 08028 Barcelona, Spain.
Cristina MiralpeixBasic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08190 Sant Cugat del Vallès, Spain.ORCID 0000-0002-0472-3754
Rafael Rivas-SantistebanCentro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CiberNed), National Institute of Health Carlos III, Valderrebollo, 5, 28031 Madrid, Spain.ORCID 0000-0002-2078-6819
Núria CasalsBasic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08190 Sant Cugat del Vallès, Spain.ORCID 0000-0002-6719-4300
Gemma NavarroCentro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CiberNed), National Institute of Health Carlos III, Valderrebollo, 5, 28031 Madrid, Spain.ORCID 0000-0003-4654-0873
Rafael FrancoCentro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CiberNed), National Institute of Health Carlos III, Valderrebollo, 5, 28031 Madrid, Spain.ORCID 0000-0003-2549-4919
Instituto de Salud Carlos III · ESUniversitat de Barcelona · ESUniversitat Internacional de Catalunya · ES

Funding

Agencia Estatal de Investigación SAF2017-84117-R and PID2020-113430RB-I00Alzheimer's Foundation of America AARFD-17-503612
6 · The paper itself

Abstract

Cannabinoids have been reported as orexigenic, i.e., as promoting food intake that, among others, is controlled by the so-called "hunger" hormone, ghrelin. The aim of this paper was to look for functional and/or molecular interactions between ghrelin GHSR1a and cannabinoid CB

Indexed as

AnimalsCannabinoidsCorpus StriatumDiet, High-FatFemaleGhrelinMiceMice, Inbred C57BLNeuronsObesityReceptor, Cannabinoid, CB2Receptors, GhrelinSignal TransductionUp-RegulationCannabinoidsGhrelinReceptor, Cannabinoid, CB2Receptors, GhrelinanorexiaG protein-coupled receptorshigh-fat dietmarihuanaobesityorexigenicpharmacologyphytocannabinoidsreceptor heteromerssignaling

Identifiers

PMID34445634
PMCPMC8396234
OpenAlexW3195370671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.