Evidence map›Paper›PMID 34445625›Full record

ArticleInternational journal of molecular sciences2021

Potent Activity of Hybrid Arthropod Antimicrobial Peptides Linked by Glycine Spacers.

Miray Tonk, James J Valdés, Alejandro Cabezas-Cruz, Andreas Vilcinskas

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. AbAMPdb: a database of Acinetobacter baumannii specific antimicrobial peptides.Database : the journal of biological databases and curation · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Miray TonkInstitute for Insect Biotechnology, Justus Liebig University of Giessen, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany.ORCID 0000-0001-8249-8452
James J ValdésInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, Branišovská 1160/31, 37005 České Budějovice, Czech Republic.ORCID 0000-0002-0237-8061
Alejandro Cabezas-CruzAnses, INRAE, Ecole Nationale Vétérinaire d'Alfort, UMR BIPAR, Laboratoire de Santé Animale, F-94700 Maisons-Alfort, France.ORCID 0000-0002-8660-730X
Andreas VilcinskasInstitute for Insect Biotechnology, Justus Liebig University of Giessen, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany.ORCID 0000-0001-8276-4968
Justus-Liebig-Universität Gießen · DEÉcole Nationale Vétérinaire d'Alfort · FRUniversity of South Bohemia in České Budějovice · CZ

Funding

European Regional Development Fund RVO: RO0516French Governments`Investissement dÀvenir ANR-10-LABX-62-IBEIDHessisches Ministerium für Wissenschaft und Kunst LOEWE Centre for Translational Biodiversity Genomics
6 · The paper itself

Abstract

Arthropod antimicrobial peptides (AMPs) offer a promising source of new leads to address the declining number of novel antibiotics and the increasing prevalence of multidrug-resistant bacterial pathogens. AMPs with potent activity against Gram-negative bacteria and distinct modes of action have been identified in insects and scorpions, allowing the discovery of AMP combinations with additive and/or synergistic effects. Here, we tested the synergistic activity of two AMPs, from the dung beetle

Indexed as

AnimalsAnti-Bacterial AgentsApoptosisArthropodsBacteriaCells, CulturedCricetinaeGlycineHemolysisKidneyMicePore Forming Cytotoxic ProteinsAnti-Bacterial AgentsGlycinePore Forming Cytotoxic Proteinsantimicrobial peptideEscherichia coliglycine spacerhybrid peptideinsectscorpion

Identifiers

PMID34445625
PMCPMC8396199
OpenAlexW3196245670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.