Evidence map›Paper›PMID 34445597›Full record

ArticleInternational journal of molecular sciences2021

ZDHHC19 Is Dispensable for Spermatogenesis, but Is Essential for Sperm Functions in Mice.

Shuai Wang, Hongjie Qiao, Pengxiang Wang, Yuan Wang, Danian Qin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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  6. TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  10. Review
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  17. The Development, Differentiation, and Toxicity in Reproduction.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Shuai WangDepartment of Physiology, Shantou University Medical College, Shantou 515041, China.
Hongjie QiaoDepartment of Physiology, Shantou University Medical College, Shantou 515041, China.
Pengxiang WangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China.
Yuan WangDepartment of Animal Sciences, College of Agriculture and Natural Resources, Michigan State University, East Lansing, MI 48824, USA.
Danian QinDepartment of Physiology, Shantou University Medical College, Shantou 515041, China.
Shantou University Medical College · CNEast China Normal University · CNMichigan State University · US

Funding

Li Ka Shing Foundation Postdoctoral Research Fellowship Program at Shantou University Medical College LD0102/510859030Natural Science Foundation of Guangdong Province of China 14162144
6 · The paper itself

Abstract

Spermatogenesis is a complicated process involving mitotically proliferating spermatogonial cells, meiotically dividing spermatocytes, and spermatid going through maturation into spermatozoa. The post-translational modifications of proteins play important roles in this biological process.

Indexed as

FertilizationSpermatogenesisSperm MotilityAcrosome ReactionAcyltransferasesAnimalsFemaleMaleMiceMice, KnockoutSpermatocytesSpermatozoaAcyltransferasesacrosome reactionfertilityspermatogenesissperm motilityZdhhc19

Identifiers

PMID34445597
PMCPMC8396176
OpenAlexW3194867599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.