Evidence map›Paper›PMID 34445580›Full record

ArticleInternational journal of molecular sciences2021

Mice Harboring a Non-Functional

Kathryn A Salvati, Ashley J Mason, Casey D Gailey, Eric J Wang, Zheng Fu, Mark P Beenhakker

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kathryn A SalvatiDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-9557-9259
Ashley J MasonDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Casey D GaileyDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Eric J WangDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-6102-7421
Zheng FuDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0003-1238-6695
Mark P BeenhakkerDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0002-4541-0201
University of Virginia · USUniversity of California, San Francisco · USUniversity of Virginia Cancer Center

Funding

Women's Oncology Program - WONP30CA044579 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Jay William FOX · 1987 to 2026
$72.1M
Signaling Mechanisms and Cellular Functions of a Ciliopathy-Associated Protein KinaseR01GM127690 · NIGMS · UNIVERSITY OF VIRGINIA · PI Zheng Fu · 2018 to 2026
$2.4M
Energy and Neural Circuit ExcitabilityR01NS099586 · NINDS · UNIVERSITY OF VIRGINIA · PI BEENHAKKER, MARK · 2016 to 2019
$1.4M
NCI NIH HHS P30 CA044579NIGMS NIH HHS R01 GM127690NIH HHS NS099586, GM127690NINDS NIH HHS R01 NS099586
6 · The paper itself

Abstract

CILK1 (ciliogenesis associated kinase 1)/ICK (intestinal cell kinase) is a highly conserved protein kinase that regulates primary cilia structure and function.

Indexed as

Disease Models, AnimalMutationPhenotypeAnimalsCiliaEpilepsyHaploinsufficiencyMiceMice, Inbred C57BLMice, KnockoutPhosphorylationProtein Serine-Threonine KinasesCilk1 protein, mouseProtein Serine-Threonine Kinasesciliopathyepilepsykinaseopisthotonosprimary ciliumseizure

Identifiers

PMID34445580
PMCPMC8396347
OpenAlexW3193925570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.