Evidence map›Paper›PMID 34445579›Full record

ArticleInternational journal of molecular sciences2021

Common Kinetic Mechanism of Abasic Site Recognition by Structurally Different Apurinic/Apyrimidinic Endonucleases.

Alexandra A Kuznetsova, Svetlana I Senchurova, Alexander A Ishchenko, Murat Saparbaev, Olga S Fedorova, Nikita A Kuznetsov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Alexandra A KuznetsovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Svetlana I SenchurovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Alexander A IshchenkoGroup Mechanisms of DNA Repair and Carcinogenesis, Equipe Labellisée LIGUE 2016, CNRS UMR9019, Gustave Roussy Cancer Campus, Université Paris-Saclay, F-94805 Villejuif, France.
Murat SaparbaevGroup Mechanisms of DNA Repair and Carcinogenesis, Equipe Labellisée LIGUE 2016, CNRS UMR9019, Gustave Roussy Cancer Campus, Université Paris-Saclay, F-94805 Villejuif, France.ORCID 0000-0002-4630-1074
Olga S FedorovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-4001-7187
Nikita A KuznetsovInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-4016-198X
Institute of Chemical Biology and Fundamental Medicine · RUCentre National de la Recherche Scientifique · FRNovosibirsk State University · RU

Funding

Electricité de France RB 2021-05French National Research Agency ANR-18-CE44-0008Russian-Government-funded project АААА-А17-117020210022-4Russian Science Foundation 19-74-10034
6 · The paper itself

Abstract

Apurinic/apyrimidinic (AP) endonucleases Nfo (

Indexed as

DNA CleavageDNA DamageBinding SitesCatalytic DomainDNA-(Apurinic or Apyrimidinic Site) LyaseDNA RepairEscherichia coliHumansKineticsMolecular Dynamics SimulationNucleic Acid ConformationNucleotidesProtein ConformationSubstrate SpecificityDNA-(Apurinic or Apyrimidinic Site) LyaseNucleotidesabasic siteapurinic/apyrimidinic endonucleaseconformational dynamicsdamaged DNADNA repairstopped-flow enzyme kinetics

Identifiers

PMID34445579
PMCPMC8396254
OpenAlexW3193617551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.