Evidence map›Paper›PMID 34445537›Full record

ArticleInternational journal of molecular sciences2021

PYTHIA: Deep Learning Approach for Local Protein Conformation Prediction.

Gabriel Cretin, Tatiana Galochkina, Alexandre G de Brevern, Jean-Christophe Gelly

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  5. VInternational journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gabriel CretinBiologie Intégrée du Globule Rouge, Université de Paris, UMR_S1134, BIGR, INSERM, 75015 Paris, France.ORCID 0000-0002-3522-7083
Tatiana GalochkinaBiologie Intégrée du Globule Rouge, Université de Paris, UMR_S1134, BIGR, INSERM, 75015 Paris, France.ORCID 0000-0002-3608-5208
Alexandre G de BrevernBiologie Intégrée du Globule Rouge, Université de Paris, UMR_S1134, BIGR, INSERM, 75015 Paris, France.ORCID 0000-0001-7112-5626
Jean-Christophe GellyBiologie Intégrée du Globule Rouge, Université de Paris, UMR_S1134, BIGR, INSERM, 75015 Paris, France.ORCID 0000-0001-5138-361X

Funding

GENCI (Grand Equipement National de Calcul Intensif) AD011011381
6 · The paper itself

Abstract

Protein Blocks (PBs) are a widely used structural alphabet describing local protein backbone conformation in terms of 16 possible conformational states, adopted by five consecutive amino acids. The representation of complex protein 3D structures as 1D PB sequences was previously successfully applied to protein structure alignment and protein structure prediction. In the current study, we present a new model, PYTHIA (

Indexed as

AlgorithmsDeep LearningNeural Networks, ComputerProtein ConformationSoftwareDatabases, ProteinHumansModels, MolecularProteinsSequence Analysis, ProteinProteinsdeep learningpredictionprotein blocksprotein structure

Identifiers

PMID34445537
PMCPMC8396346

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.