Evidence map›Paper›PMID 34445521›Full record

ReviewInternational journal of molecular sciences2021

Stimuli-Responsive Poly(aspartamide) Derivatives and Their Applications as Drug Carriers.

Guangyan Zhang, Hui Yi, Chenhui Bao

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Guangyan ZhangSchool of Materials and Chemical Engineering, Hubei University of Technology, Wuhan 430068, China.ORCID 0000-0003-1513-0003
Hui YiSchool of Materials and Chemical Engineering, Hubei University of Technology, Wuhan 430068, China.
Chenhui BaoSchool of Materials and Chemical Engineering, Hubei University of Technology, Wuhan 430068, China.

Funding

Research Foundation of Hubei Provincial Key Laboratory of Green Materials for Light Industry and Collaborative Innovation Center of Green Light-weight Materials and Processing 201907B08
6 · The paper itself

Abstract

Poly(aspartamide) derivatives, one kind of amino acid-based polymers with excellent biocompatibility and biodegradability, meet the key requirements for application in various areas of biomedicine. Poly(aspartamide) derivatives with stimuli-responsiveness can usually respond to external stimuli to change their chemical or physical properties. Using external stimuli such as temperature and pH as switches, these smart poly(aspartamide) derivatives can be used for convenient drug loading and controlled release. Here, we review the synthesis strategies for preparing these stimuli-responsive poly(aspartamide) derivatives and the latest developments in their applications as drug carriers.

Indexed as

Aspartic AcidDelayed-Action PreparationsDrug CarriersHydrogen-Ion ConcentrationPolymersTemperatureAspartic AcidDelayed-Action PreparationsDrug Carrierspoly(aspartamide)Polymerscontrolled drug releasedrug carrierdrug-loadinghydrogelnanoparticlespoly(aspartamide) derivativespolymer-drug conjugatestimuli-responsive

Identifiers

PMID34445521
PMCPMC8396293

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.