Evidence map›Paper›PMID 34445453›Full record

ArticleInternational journal of molecular sciences2021

Conditional Inactivation of Limbic Neuropeptide Y-1 Receptors Increases Vulnerability to Diet-Induced Obesity in Male Mice.

Silvia Paterlini, Riccardo Panelli, Laura Gioiosa, Stefano Parmigiani, Paolo Franceschini, Ilaria Bertocchi, Alessandra Oberto, Alessandro Bartolomucci, Carola Eva, Paola Palanza

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Silvia PaterliniUnit of Neuroscience, Department of Medicine and Surgery, University of Parma, 43100 Parma, Italy.ORCID 0000-0001-9580-5458
Riccardo PanelliUnit of Neuroscience, Department of Medicine and Surgery, University of Parma, 43100 Parma, Italy.
Laura GioiosaUnit of Neuroscience, Department of Medicine and Surgery, University of Parma, 43100 Parma, Italy.
Stefano ParmigianiDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43100 Parma, Italy.
Paolo FranceschiniUnit of Neuroscience, Department of Medicine and Surgery, University of Parma, 43100 Parma, Italy.
Ilaria BertocchiNeuroscience Institute of the Cavalieri-Ottolenghi Foundation, 10043 Orbassano, Italy.ORCID 0000-0002-2880-716X
Alessandra ObertoNeuroscience Institute of the Cavalieri-Ottolenghi Foundation, 10043 Orbassano, Italy.ORCID 0000-0001-7799-4769
Alessandro BartolomucciDepartment of Physiology, University of Minnesota, Minneapolis, MN 55455, USA.
Carola EvaNeuroscience Institute of the Cavalieri-Ottolenghi Foundation, 10043 Orbassano, Italy.
Paola PalanzaUnit of Neuroscience, Department of Medicine and Surgery, University of Parma, 43100 Parma, Italy.ORCID 0000-0003-2873-4260
University of Parma · ITNeuroscience Institute · ITUniversity of Minnesota · US

Funding

Compagnia di San Paolo Neuroscience ProgramFondazione Cariplo 2013-0786Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2008 PLKP3E_002Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2010 7MSMA4_005
6 · The paper itself

Abstract

NPY and its Y1 cognate receptor (Y1R) have been shown to be involved in the regulation of stress, anxiety, depression and energy homeostasis. We previously demonstrated that conditional knockout of

Indexed as

Diet, High-FatAnimalsEatingGene Knockout TechniquesGlucose IntoleranceLimbic SystemMaleMiceObesityReceptors, Neuropeptide YNpy1r protein, mouseReceptors, Neuropeptide Yfood intakeglucose intolerancehigh fat dietNPYobesityY1R

Identifiers

PMID34445453
PMCPMC8395771
OpenAlexW3195229682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.