Evidence map›Paper›PMID 34445407›Full record

ArticleInternational journal of molecular sciences2021

Granuloma Formation in a

Rodrigo Prieto-Bermejo, Marta Romo-González, Alejandro Pérez-Fernández, María Carmen García-Macías, Carmen Sánchez-Bernal, Ignacio García-Tuñón, Jesús Sánchez-Yagüe, Manuel Sánchez-Martín, Ángel Hernández-Hernández

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Egg-driven immunosuppression and granuloma zonation in Peyer's patches of mice withFrontiers in cellular and infection microbiology · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rodrigo Prieto-BermejoDepartamento de Bioquímica y Biología Molecular, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-2445-7262
Marta Romo-GonzálezDepartamento de Bioquímica y Biología Molecular, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-2884-3398
Alejandro Pérez-FernándezDepartamento de Bioquímica y Biología Molecular, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-7862-7952
María Carmen García-MacíasUnidad de Patología Molecular Comparada, Centro de Investigación del Cáncer-IBMCC (USAL-CSIC), 37007 Salamanca, Spain.ORCID 0000-0002-5929-4926
Carmen Sánchez-BernalDepartamento de Bioquímica y Biología Molecular, Universidad de Salamanca, 37007 Salamanca, Spain.
Ignacio García-TuñónUnidad de Diagnóstico Molecular y Celular del Cáncer, Centro de Investigación del Cáncer-IBMCC (USAL-CSIC), 37007 Salamanca, Spain.ORCID 0000-0003-4758-2151
Jesús Sánchez-YagüeDepartamento de Bioquímica y Biología Molecular, Universidad de Salamanca, 37007 Salamanca, Spain.
Manuel Sánchez-MartínIBSAL (Instituto de Investigación Biomédica de Salamanca), 37007 Salamanca, Spain.ORCID 0000-0001-8370-1336
Ángel Hernández-HernándezDepartamento de Bioquímica y Biología Molecular, Universidad de Salamanca, 37007 Salamanca, Spain.ORCID 0000-0003-0827-7963
Universidad de Salamanca · ESCentro de Investigación del Cáncer · ES

Funding

Consejería de Educación, Junta de Castilla y León SA077P20
6 · The paper itself

Abstract

Haematopoiesis is a paradigm of cell differentiation because of the wide variety and overwhelming number of mature blood cells produced daily. Under stress conditions, the organism must adapt to a boosted demand for blood cells. Chronic granulomatous disease (CGD) is a genetic disease caused by inactivating mutations that affect the phagocyte oxidase. Besides a defective innate immune system, CGD patients suffer from recurrent hyper-inflammation episodes, circumstances upon which they must face emergency haematopoiesis. The targeting of

Indexed as

AnimalsB-LymphocytesCell LineageCRISPR-Cas SystemsCytochrome b GroupDisease Models, AnimalFemaleGene Knockdown TechniquesGranulomatous Disease, ChronicHumansHyperplasiaMaleMiceMyeloid CellsNADPH OxidasesCyba protein, mouseCytochrome b GroupNADPH Oxidaseschronic granulomatous diseaseimmuneinflammationmurine modelmyeloproliferative diseaseNADPH oxidase

Identifiers

PMID34445407
PMCPMC8395996
OpenAlexW3194303626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.