Evidence map›Paper›PMID 34445390›Full record

ArticleInternational journal of molecular sciences2021

Role of Nuclear Factor of Activated T Cells (NFAT) Pathway in Regulating Autophagy and Inflammation in Retinal Pigment Epithelial Cells.

Hsuan-Yeh Pan, Ashley V Ladd, Manas R Biswal, Mallika Valapala

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  8. Role of TFEB in Diseases Associated with Lysosomal Dysfunction.Advances in experimental medicine and biology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hsuan-Yeh PanSchool of Optometry, Indiana University, Bloomington, IN 47405, USA.
Ashley V LaddSchool of Optometry, Indiana University, Bloomington, IN 47405, USA.
Manas R BiswalDepartment of Pharmaceutical Sciences, Taneja College of Pharmacy, University of South Florida, Tampa, FL 33612, USA.ORCID 0000-0002-9685-2923
Mallika ValapalaSchool of Optometry, Indiana University, Bloomington, IN 47405, USA.
Indiana University Bloomington · USUniversity of South Florida · US

Funding

Short-Term Research Training For Optometry StudentsT35EY013937 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI MILLER, DONALD T · 2001 to 2021
$717k
NEI NIH HHS T35 EY013937
6 · The paper itself

Abstract

Nuclear factor of activated T cells (NFAT) family of transcription factors are substrates of calcineurin and play an important role in integrating Ca

Indexed as

AutophagyBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCell LineEpithelial CellsGene Expression RegulationHumansInterleukin-6Interleukin-8LipopolysaccharidesNFATC Transcription FactorsOligopeptidesRetinal Pigment EpitheliumSignal TransductionBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCXCL8 protein, humanIL6 protein, humanInterleukin-6Interleukin-8LipopolysaccharidesNFATC Transcription FactorsOligopeptidesTFEB protein, humanVIVIT peptideautophagycalcineurinlysosomal functionnuclear factor of activated in T cells (NFAT)retinal pigment epithelium (RPE)transcription factor EB

Identifiers

PMID34445390
PMCPMC8395439
OpenAlexW3192603863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.