ArticleInternational journal of molecular sciences2021
Polyvinyl-Pyrrolidone-Coated Silver Nanoparticles-The Colloidal, Chemical, and Biological Consequences of Steric Stabilization under Biorelevant Conditions.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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Who cites it
47 citing papers in PubMed.
- Enhanced anticancer efficacy ofMaterials today. Bio · 2026Article
- Cationic carbon dot-silver nanohybrids with enhanced stability and redox control.Discover nano · 2026Article
- Green Synthesis of Silver Nanoparticles fromLife (Basel, Switzerland) · 2026Article
- Plasmonic and surface-enhanced Raman nanobiosensors for quantitative molecular detection.Discover nano · 2026Review
- Ultrastructural changes and defense strategy of yellow lupine during silver nanoparticle and Fusarium oxysporum interaction.Scientific reports · 2026Article
- Article
- Scalable Synthesis of High-Density Ultrafine Spherical Silver Powders.Materials (Basel, Switzerland) · 2026Article
- Effect of polyvinylpyrrolidone molecular weight and concentration on its dual role in the synthesis, stability and antimicrobial activity of silver nanoparticles.Scientific reports · 2026Article
- Silver Nanoparticles in Antibacterial Research: Mechanisms, Applications, and Emerging Perspectives.International journal of molecular sciences · 2026Review
- Cyclodextrin-Based Nanocarriers for 5-Fluorouracil: Cholesteryl Modification Enhances Antitumor Activity Against Colorectal Cancer Cells.International journal of nanomedicine · 2026Article
- The Impact of the Reducing Agent on the Cytotoxicity and Selectivity Index of Silver Nanoparticles in Leukemia and Healthy Cells.Nanomaterials (Basel, Switzerland) · 2025Article
- A Focus on Thermal Durability and Oxidation Resistance and Morphology of Polymer Capped Copper Particles Through a Synthesis-Driven, Precursor-Influenced Approach.Nanomaterials (Basel, Switzerland) · 2025Article
- Sensitive chemiluminescent determination of CYFRA 21-1 as a lung cancer marker using PVP/NiO-supported luminol@ZIF-67-aptamer composite.Mikrochimica acta · 2025Article
- Protein Corona as a Result of Interaction of Protein Molecules with Inorganic Nanoparticles.International journal of molecular sciences · 2025Review
- Versatile Liquid Metal Composite Inks for Printable, Durable, and Ultra-Stretchable Electronics.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Green Synthesis of Silver Nanoparticles and Polymeric Nanofiber Composites: Fabrications, Mechanisms, and Applications.Polymers · 2025Review
- Tailoring innovative silver nanoparticles for modern medicine: The importance of size and shape control and functional modifications.Materials today. Bio · 2025Review
- Article
- New approach methodologies for in vitro toxicity screening of nanomaterial using a pulmonary three-dimensional floating extracellular matrix model.Journal of biological engineering · 2025Article
- Pesticide effects of highly stable green synthesized silver nanocomposites to be used in organic tomato crops.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
(1) Background: Several properties of silver nanoparticles (AgNPs), such as cytotoxic, anticancer, and antimicrobial activities, have been subjects of intense research; however, important aspects such as nanoparticle aggregation are generally neglected, although a decline in colloidal stability leads to a loss of the desired biological activities. Colloidal stability is affected by pH, ionic strength, or a plethora of biomolecules that interact with AgNPs under biorelevant conditions. (2) Methods: As only a few studies have focused on the relationship between aggregation behavior and the biological properties of AgNPs, here, we have systematically evaluated this issue by completing a thorough analysis of sterically (via polyvinyl-pyrrolidone (PVP)) stabilized AgNPs that were subjected to different circumstances. We assessed ultraviolet-visible light absorption, dynamic light scattering, zeta potential measurements, in vitro cell viability, and microdilution assays to screen both colloidal stability as well as bioactivity. (3) Results: The results revealed that although PVP provided outstanding biorelevant colloidal stability, the chemical stability of AgNPs could not be maintained completely with this capping material. (4) Conclusion: These unexpected findings led to the realization that stabilizing materials have more profound importance in association with biorelevant applications of nanomaterials than just being simple colloidal stabilizers.
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Registered trials
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