Evidence map›Paper›PMID 34445318›Full record

ArticleInternational journal of molecular sciences2021

Serotonergic-Muscarinic Interaction within the Prefrontal Cortex as a Novel Target to Reverse Schizophrenia-Related Cognitive Symptoms.

Paulina Cieślik, Adrianna Radulska, Grzegorz Burnat, Leszek Kalinowski, Joanna M Wierońska

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Paulina CieślikDepartment of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Kraków, Poland.ORCID 0000-0003-1182-573X
Adrianna RadulskaDepartment of Medical Laboratory Diagnostics-Fahrenheit Biobank BBMRI.pl, Medical University of Gdańsk, 7 Dębinki Street, 80-211 Gdańsk, Poland.
Grzegorz BurnatDepartment of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Kraków, Poland.ORCID 0000-0002-2300-0850
Leszek KalinowskiDepartment of Medical Laboratory Diagnostics-Fahrenheit Biobank BBMRI.pl, Medical University of Gdańsk, 7 Dębinki Street, 80-211 Gdańsk, Poland.
Joanna M WierońskaDepartment of Medical Laboratory Diagnostics-Fahrenheit Biobank BBMRI.pl, Medical University of Gdańsk, 7 Dębinki Street, 80-211 Gdańsk, Poland.
Gdańsk Medical University · PLMaj Institute of Pharmacology · PLGdańsk University of Technology · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego DIR/WK/2017/01Narodowe Centrum Nauki 2018/31/N/NZ7/03646
6 · The paper itself

Abstract

Recent studies revealed that the activation of serotonergic 5-HT

Indexed as

AnimalsBenzamidesBlood-Brain BarrierCholinergic AgentsCognitive DysfunctionDizocilpine MaleateMaleMaze LearningMicePiperidinesPrefrontal CortexPyridinesPyrimidinesReceptors, MuscarinicReceptors, SerotoninSchizophrenia3-amino-N-(4-methoxybenzyl)-4,6-dimethylthieno(2,3-b)pyridine-2-carboxamide3-chloro-4-fluorophenyl-(4-fluoro-4-(((5-methylpyrimidin-2-ylmethyl)amino)methyl)piperidin-1-yl)methanoneBenzamidesCholinergic AgentsDizocilpine MaleatePiperidinesPyridinesPyrimidinesReceptors, MuscarinicReceptors, SerotoninSerotonin Receptor AgonistsThiophenesVU03570175-HT1Acognitive deficitsM1M4M5muscarinic receptorsschizophrenia

Identifiers

PMID34445318
PMCPMC8395335
OpenAlexW3190332298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.