Evidence map›Paper›PMID 34445299›Full record

ArticleInternational journal of molecular sciences2021

Keratin-Alginate Sponges Support Healing of Partial-Thickness Burns.

Zi Kuang Moay, Luong T H Nguyen, Pietradewi Hartrianti, Declan P Lunny, David Leavesley, Yee Onn Kok, Si Jack Chong, Alvin Wen Choong Chua, Shang-Ian Tee, Kee Woei Ng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Zi Kuang MoaySchool of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore.ORCID 0000-0003-2231-5428
Luong T H NguyenWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 West Woodruff, Columbus, OH 43210, USA.
Pietradewi HartriantiDepartment of Pharmacy, School of Life Sciences, Indonesia International Institute for Life Sciences, Jalan Pulomas Barat Kav 88, Jakarta 13210, Indonesia.ORCID 0000-0002-5315-6741
Declan P LunnySkin Research Institute of Singapore-Agency for Science Technology and Research, 11 Mandalay Road, Clinical Sciences Building, Singapore 308232, Singapore.
David LeavesleySkin Research Institute of Singapore-Agency for Science Technology and Research, 11 Mandalay Road, Clinical Sciences Building, Singapore 308232, Singapore.ORCID 0000-0002-1033-5459
Yee Onn KokDepartment of Plastic Reconstructive & Aesthetic Surgery, Singapore General Hospital, Singapore 169856, Singapore.
Si Jack ChongDepartment of Plastic Reconstructive & Aesthetic Surgery, Singapore General Hospital, Singapore 169856, Singapore.
Alvin Wen Choong ChuaDivision of Musculoskeletal Sciences, Singapore General Hospital, Singapore 169856, Singapore.
Shang-Ian TeeNational Skin Centre, 1 Mandalay Road, Singapore 308205, Singapore.
Kee Woei NgSchool of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore.ORCID 0000-0002-7276-3563
Agency for Science, Technology and Research · SGSingapore General Hospital · SGIndonesia International Institute for Life Sciences · IDNanyang Technological University · SGNational Skin Centre · SGThe Ohio State University · US

Funding

Agency for Science, Technology and Research H17/01/a0/0L9
6 · The paper itself

Abstract

Deep partial-thickness burns damage most of the dermis and can cause severe pain, scarring, and mortality if left untreated. This study serves to evaluate the effectiveness of crosslinked keratin-alginate composite sponges as dermal substitutes for deep partial-thickness burns. Crosslinked keratin-alginate sponges were tested for the ability to support human dermal fibroblasts in vitro and to support the closure and healing of partial-thickness burn wounds in

Indexed as

Wound HealingAlginatesAnimalsBandages, HydrocolloidBurnsCells, CulturedDermisHumansHydrogelsKeratinsMaleMaterials TestingSeverity of Illness IndexSkinSwineAlginatesHydrogelsKeratinsfibroblasthuman hair keratinporcine burn woundsspongewound healing

Identifiers

PMID34445299
PMCPMC8395243
OpenAlexW3189038958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.