Evidence map›Paper›PMID 34445281›Full record

ArticleInternational journal of molecular sciences2021

Pyranoanthocyanins Interfering with the Quorum Sensing of

Patrícia Coelho, Joana Oliveira, Iva Fernandes, Paula Araújo, Ana Rita Pereira, Paula Gameiro, Lucinda J Bessa

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Anti-QS Strategies AgainstMicroorganisms · 2025
    Review
  4. DisarmingPathogens (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Review
  7. Structural characteristics, functions, and counteracting strategies of biofilms inComputational and structural biotechnology journal · 2025
    Review
  8. Antimicrobial and Antibiofilm Potential ofPlants (Basel, Switzerland) · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. The Molecular Architecture ofMarine drugs · 2022
    Review
  14. DNase inhibits early biofilm formation inFrontiers in cellular and infection microbiology · 2022
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Patrícia CoelhoLAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.ORCID 0000-0002-4390-5497
Joana OliveiraLAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.ORCID 0000-0002-9996-1463
Iva FernandesLAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.ORCID 0000-0003-2297-0086
Paula AraújoLAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.
Ana Rita PereiraLAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.ORCID 0000-0002-9779-2678
Paula GameiroLAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.ORCID 0000-0002-4747-6853
Lucinda J BessaLAQV-REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal.ORCID 0000-0001-8339-1964
Universidade do Porto · PT

Funding

Fundação para a Ciência e a Tecnologia UIDB/50006/2020Fundação para a Ciência e a Tecnologia and European Regional Development Fund PTDC/QUI-OUT/29013/2017
6 · The paper itself

Abstract

Bacterial quorum sensing (QS) is a cell-cell communication system that regulates several bacterial mechanisms, including the production of virulence factors and biofilm formation. Thus, targeting microbial QS is seen as a plausible alternative strategy to antibiotics, with potentiality to combat multidrug-resistant pathogens. Many phytochemicals with QS interference activity are currently being explored. Herein, an extract and a compound of bioinspired origin were tested for their ability to inhibit biofilm formation and interfere with the expression of QS-related genes in

Indexed as

AnthocyaninsBiofilmsPseudomonas aeruginosaQuorum SensingStaphylococcus aureusAnthocyaninsbiofilmsPseudomonas aeruginosapyranoanthocyaninsquorum sensingreverse transcription-quantitative polymerase chain reaction (RT-qPCR)Staphylococcus aureus

Identifiers

PMID34445281
PMCPMC8395250
OpenAlexW3190038515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.