Evidence map›Paper›PMID 34445269›Full record

ArticleInternational journal of molecular sciences2021

Chromophore of an Enhanced Green Fluorescent Protein Can Play a Photoprotective Role Due to Photobleaching.

Joanna Krasowska, Katarzyna Pierzchała, Agnieszka Bzowska, László Forró, Andrzej Sienkiewicz, Beata Wielgus-Kutrowska

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Fluorescent proteins generate a genetic color polymorphism and counteract oxidative stress in intertidal sea anemones.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Joanna KrasowskaDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warsaw, Poland.ORCID 0000-0001-7201-4944
Katarzyna PierzchałaLaboratory for Functional and Metabolic Imaging (LIFMET), Institute of Physics (IPHYS), School of Basic Sciences (SB), Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
Agnieszka BzowskaDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warsaw, Poland.ORCID 0000-0002-3976-429X
László ForróLaboratory of Physics of Complex Matter (LPMC), Institute of Physics (IPHYS), School of Basic Sciences (SB), Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.ORCID 0000-0002-3513-328X
Andrzej SienkiewiczLaboratory of Physics of Complex Matter (LPMC), Institute of Physics (IPHYS), School of Basic Sciences (SB), Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.ORCID 0000-0003-3527-7379
Beata Wielgus-KutrowskaDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warsaw, Poland.ORCID 0000-0002-5049-864X
École Polytechnique Fédérale de Lausanne · CHUniversity of Warsaw · PL

Funding

European Regional Development Fund within the Innovation Economy Operational Program POIG.02.02.00-00-025/09/ and POIG.02.01.00-14-122/09European Union within European Social Fund, under the Human Capital Operational Programme UDA-POKL.04.01.01-00-072/09-00
6 · The paper itself

Abstract

Under stress conditions, elevated levels of cellular reactive oxygen species (ROS) may impair crucial cellular structures. To counteract the resulting oxidative damage, living cells are equipped with several defense mechanisms, including photoprotective functions of specific proteins. Here, we discuss the plausible ROS scavenging mechanisms by the enhanced green fluorescent protein, EGFP. To check if this protein could fulfill a photoprotective function, we employed electron spin resonance (ESR) in combination with spin-trapping. Two organic photosensitizers, rose bengal and methylene blue, as well as an inorganic photocatalyst, nano-TiO

Indexed as

PhotobleachingElectron Spin Resonance SpectroscopyGreen Fluorescent ProteinsSinglet OxygenSuperoxidesenhanced green fluorescent proteinGreen Fluorescent ProteinsSinglet OxygenSuperoxidesEGFPelectron spin resonancephotoprotectionreactive oxygen speciesscavengersinglet oxygenspin trappingsuperoxide radicals

Identifiers

PMID34445269
PMCPMC8395242
OpenAlexW3189798804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.