Evidence map›Paper›PMID 34445232›Full record

ArticleInternational journal of molecular sciences2021

Effect of Active Lengthening and Shortening on Small-Angle X-ray Reflections in Skinned Skeletal Muscle Fibres.

Venus Joumaa, Ian C Smith, Atsuki Fukutani, Timothy R Leonard, Weikang Ma, Srboljub M Mijailovich, Thomas C Irving, Walter Herzog

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Muscle Diffraction at the Life Science X-ray Scattering Beamline.bioRxiv : the preprint server for biology · 2026
    Article
  3. Popping the hood of muscle motors using time-resolved, small-angle X-ray diffraction.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. The distinctive mechanical and structural signatures of residual force enhancement in myofibers.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Venus JoumaaHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada.
Ian C SmithHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada.ORCID 0000-0001-5269-1710
Atsuki FukutaniFaculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.ORCID 0000-0002-8572-7940
Timothy R LeonardHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada.
Weikang MaThe Biophysics Collaborative Access Team (BioCAT), Department of Biological Sciences, Illinois Institute of Technology, Chicago, IL 60616, USA.ORCID 0000-0001-9535-7114
Srboljub M MijailovichDepartment of Biological Sciences, Illinois Institute of Technology, Chicago, IL 60616, USA.
Thomas C IrvingThe Biophysics Collaborative Access Team (BioCAT), Department of Biological Sciences, Illinois Institute of Technology, Chicago, IL 60616, USA.ORCID 0000-0003-4848-3323
Walter HerzogHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada.
University of Calgary · CAIllinois Institute of Technology · USRitsumeikan University · JP

Funding

The Biophysics Collaborative Access Team (User Training and Outreach)P30GM138395 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI THOMAS C IRVING · 2021 to 2026
$16.5M
Time resolved SAXS studies on the RP2/Arl3 complex pp.484-485P41GM103622 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI IRVING, THOMAS C · 2012 to 2020
$11.9M
CIHR CIHR Canada Research Chair 950-200955CIHR CIHR Foundation Grant FDN-143341Killam Trusts Project number 10001203NIGMS NIH HHS 9 P41 GM103622NIGMS NIH HHS P30 GM138395NIGMS NIH HHS P41 GM103622
6 · The paper itself

Abstract

Our purpose was to use small-angle X-ray diffraction to investigate the structural changes within sarcomeres at steady-state isometric contraction following active lengthening and shortening, compared to purely isometric contractions performed at the same final lengths. We examined force, stiffness, and the 1,0 and 1,1 equatorial and M3 and M6 meridional reflections in skinned rabbit psoas bundles, at steady-state isometric contraction following active lengthening to a sarcomere length of 3.0 µm (15.4% initial bundle length at 7.7% bundle length/s), and active shortening to a sarcomere length of 2.6 µm (15.4% bundle length at 7.7% bundle length/s), and during purely isometric reference contractions at the corresponding sarcomere lengths. Compared to the reference contraction, the isometric contraction after active lengthening was associated with an increase in force (i.e., residual force enhancement) and M3 spacing, no change in stiffness and the intensity ratio I

Indexed as

Muscle ContractionMuscle RelaxationScattering, Small AngleX-Ray DiffractionAnimalsMuscle Fibers, SkeletalRabbitsequatorial X-ray reflectionsforce depressionlattice spacingmeridional X-ray reflectionsresidual force enhancementshift in massstiffness

Identifiers

PMID34445232
PMCPMC8395229
OpenAlexW3191953418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.