Evidence map›Paper›PMID 34445176›Full record

ArticleInternational journal of molecular sciences2021

Promising Anticancer Activity of [Bis(1,8-quinolato)palladium (II)] Alone and in Combination.

Md Nur Alam, Mohammad Ali Moni, Jun Q Yu, Philip Beale, Peter Turner, Nick Proschogo, Mohammad Azizur Rahman, M Pear Hossain, Fazlul Huq

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Md Nur AlamDepartment of Pharmacy, Faculty of Biological Sciences, Jahangirnagar University, Dhaka 1342, Bangladesh.
Mohammad Ali MoniSchool of Health and Rehabilitation Sciences, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0003-0756-1006
Jun Q YuDiscipline of Pathology, School of Medicine, The University of Sydney, Sydney, NSW 2006, Australia.
Philip BealeSydney Cancer Centre, Concord Hospital, Sydney, NSW 2139, Australia.
Peter TurnerSchool of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Nick ProschogoSchool of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Mohammad Azizur RahmanDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, Jahangirnagar University, Dhaka 1342, Bangladesh.
M Pear HossainDepartment of Statistics, Bangabandhu Sheikh Mujibur Rahman Science & Technology University, Gopalganj 8100, Bangladesh.ORCID 0000-0001-5247-4820
Fazlul HuqSchool of Medical Sciences, The University of Sydney, Kenthurst , NSW 2156, Australia.
The University of Sydney · AUJahangirnagar University · BDConcord Repatriation General Hospital · AUGopalganj Science and Technology University · BDThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to similar coordination chemistry of palladium and platinum, a large number of palladium compounds as well have been investigated for their anticancer activity. In the present study, we describe synthesis, characterization, and anticancer activity of palladium complex [Bis(1,8-quinolato)palladium (II)], coded as NH3 against seven different cancer cell lines. NH3 is found to have higher antitumor activity than cisplatin against both parent ovarian A2780 cell line and cisplatin-resistant cell lines. Also, NH3 has the lower IC

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorCoordination ComplexesHumansMaleMiceModels, MolecularNeoplasmsPalladiumProtein Interaction MapsQuinolinic AcidAntineoplastic AgentsCoordination ComplexesPalladiumQuinolinic Acid8-Hydroxyquinolinecancerpalladiumproteomics

Identifiers

PMID34445176
PMCPMC8395214
OpenAlexW3110573736

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.