Evidence map›Paper›PMID 34445142›Full record

ArticleInternational journal of molecular sciences2021

Der f 38 Is a Novel TLR4-Binding Allergen Related to Allergy Pathogenesis from

Geunyeong Kim, Minhwa Hong, Ayesha Kashif, Yujin Hong, Beom-Seok Park, Ji-Young Mun, Hyosun Choi, Ji-Sook Lee, Eun-Ju Yang, Ran-Sook Woo and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. The role of neutrophils in allergic disease.Clinical and experimental immunology · 2025
    Review
  4. Article
  5. New approaches to immunotherapy in house dust mite allergy.Clinical and experimental pediatrics · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Geunyeong KimDepartment of Senior Healthcare, Eulji University, Uijeongbu 11759, Korea.
Minhwa HongDepartment of Senior Healthcare, Eulji University, Uijeongbu 11759, Korea.
Ayesha KashifDepartment of Senior Healthcare, Eulji University, Uijeongbu 11759, Korea.
Yujin HongDepartment of Senior Healthcare, Eulji University, Uijeongbu 11759, Korea.
Beom-Seok ParkDepartment of Biomedical Laboratory Science, College of Health Science, Eulji University, Seongnam 13135, Korea.
Ji-Young MunNeural Circuit Research Group, Korea Brain Research Institute, Daegu 41068, Korea.
Hyosun ChoiNanobioimaging Center, National Instrumentation Center for Environmental Management, Seoul National University, Seoul 08826, Korea.
Ji-Sook LeeDepartment of Clinical Laboratory Science, Wonkwang Health Science University, Iksan 54538, Korea.
Eun-Ju YangDepartment of Clinical Laboratory Science, Daegu Haany University, Gyeongsan 38610, Korea.ORCID 0000-0002-3674-8163
Ran-Sook WooDepartment of Anatomy and Neuroscience, Eulji University School of Medicine, Daejeon 34824, Korea.
Soo-Jin LeeDepartment of Pediatrics, Eulji University School of Medicine, Daejeon 34824, Korea.
Minseo YangDepartment of Biomedical Laboratory Science, College of Health Science, Eulji University, Uijeongbu 11759, Korea.
In-Sik KimDepartment of Senior Healthcare, Eulji University, Uijeongbu 11759, Korea.
Eulji University · KRDaegu Haany University · KRKorea Brain Research Institute · KRSeoul National University · KRWonKwang Health Science University · KR

Funding

Eulji University 2020-1
6 · The paper itself

Abstract

It is difficult to treat allergic diseases including asthma completely because its pathogenesis remains unclear. House dust mite (HDM) is a critical allergen and Toll-like receptor (TLR) 4 is a member of the toll-like receptor family, which plays an important role in allergic diseases. The purpose of this study was to characterize a novel allergen, Der f 38 binding to TLR4, and unveil its role as an inducer of allergy. Der f 38 expression was detected in the body and feces of

Indexed as

AllergensAmino Acid SequenceAnimalsAntigens, DermatophagoidesArthropod ProteinsDermatophagoides farinaeEpitopesFemaleHumansHypersensitivityImmunoglobulin EMiceMice, Inbred BALB CMice, KnockoutProtein BindingPyroglyphidaeAllergensAntigens, DermatophagoidesArthropod ProteinsEpitopesImmunoglobulin ETLR4 protein, humanToll-Like Receptor 4allergyDer f 38house dust miteTLR4

Identifiers

PMID34445142
PMCPMC8395149
OpenAlexW3189724140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.