Evidence map›Paper›PMID 34445039›Full record

ArticleNutrients2021

Extensive Study of Breast Milk and Infant Growth: Protocol of the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF).

Laurentya Olga, Clive J Petry, Janna A van Diepen, Philippa M Prentice, Ieuan A Hughes, Jacques Vervoort, Jos Boekhorst, Maciej Chichlowski, Gabriele Gross, David B Dunger and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Laurentya OlgaDepartment of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.
Clive J PetryDepartment of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0002-6642-9825
Janna A van DiepenDepartment of Internal Medicine and Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6545 CJ Nijmegen, The Netherlands.
Philippa M PrenticeDepartment of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.
Ieuan A HughesDepartment of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.
Jacques VervoortLaboratory of Biochemistry, Wageningen University, 6708 PB Wageningen, The Netherlands.
Jos BoekhorstNIZO Food Research BV, 6718 ZB Ede, The Netherlands.
Maciej ChichlowskiDepartment of Medical Affairs, Mead Johnson Nutrition, Evansville, IN 47721, USA.ORCID 0000-0002-6004-2195
Gabriele GrossDepartment of Internal Medicine and Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6545 CJ Nijmegen, The Netherlands.
David B DungerDepartment of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0002-2566-9304
Ken K OngDepartment of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK.ORCID 0000-0003-4689-7530
University of Cambridge · GBRadboud University Nijmegen · NLMead Johnson (United States) · USNederlands Instituut Voor Zuivel Oonderzoek · NLWageningen University & Research · NL

Funding

Medical Research Council G1001995Medical Research Council MC_UU_00006/2Medical Research Council MC_UU_12015/2Medical Research Council Unit programmes: MC_UU_12015/2 and MC_UU_00006/2National Institute for Health Research/Wellcome Trust Clinical Research Facility at Cambridge University Hospitals NHS Foundation Trust NANIHR Cambridge Comprehensive Biomedical Research Centre NAReckitt/Mead Johnson Nutrition Institute NAWellcome Trust
6 · The paper itself

Abstract

Growth and nutrition during early life have been strongly linked to future health and metabolic risks. The Cambridge Baby Growth Study (CBGS), a longitudinal birth cohort of 2229 mother-infant pairs, was set up in 2001 to investigate early life determinant factors of infant growth and body composition in the UK setting. To carry out extensive profiling of breastmilk intakes and composition in relation to infancy growth, the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF) was established upon the original CBGS. The strict inclusion criteria were applied, focusing on a normal birth weight vaginally delivered infant cohort born of healthy and non-obese mothers. Crucially, only infants who were exclusively breastfed for the first 6 weeks of life were retained in the analysed study sample. At each visit from birth, 2 weeks, 6 weeks, and then at 3, 6, 12, 24, and 36 months, longitudinal anthropometric measurements and blood spot collections were conducted. Infant body composition was assessed using air displacement plethysmography (ADP) at 6 weeks and 3 months of age. Breast milk was collected for macronutrients and human milk oligosaccharides (HMO) measurements. Breast milk intake volume was also estimated, as well as sterile breastmilk and infant stool collection for microbiome study.

Indexed as

Breast FeedingChild DevelopmentMilk, HumanNutritive ValueAdiposityAge FactorsBody HeightChild, PreschoolEnglandFemaleGastrointestinal MicrobiomeHeadHumansInfantInfant, NewbornInfant Nutritional Physiological Phenomenabreastfeedingbreast milkbreast milk nutrientschildhood obesitycohort profileearly lifehuman milk oligosaccharidesinfant growthinfant nutritionprevention

Identifiers

PMID34445039
PMCPMC8400677
OpenAlexW3196157821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.