Evidence map›Paper›PMID 34444997›Full record

ArticleNutrients2021

Association of the Maternal Gut Microbiota/Metabolome with Cord Blood CCL17.

Hiromi Tanabe, Kenichi Sakurai, Yumiko Nakanishi, Tamotsu Kato, Yohei Kawasaki, Taiji Nakano, Fumiya Yamaide, Naoko Taguchi-Atarashi, Yuki Shiko, Ikumi Takashima and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Hiromi TanabeCenter for Preventive Medical Sciences, Chiba University, Chiba 263-8522, Japan.ORCID 0000-0002-2712-624X
Kenichi SakuraiCenter for Preventive Medical Sciences, Chiba University, Chiba 263-8522, Japan.
Yumiko NakanishiLaboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa 230-0045, Japan.
Tamotsu KatoLaboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa 230-0045, Japan.
Yohei KawasakiFaculty of Nursing, Japanese Red Cross College of Nursing, Tokyo 150-0012, Japan.
Taiji NakanoDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Fumiya YamaideDepartment of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.ORCID 0000-0002-2916-9710
Naoko Taguchi-AtarashiLaboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa 230-0045, Japan.
Yuki ShikoBiostatistics Section, Clinical Research Center, Chiba University Hospital, Chiba 260-8677, Japan.ORCID 0000-0002-3959-9343
Ikumi TakashimaData Science Office, Clinical Research Promotion Center, University of Tokyo Hospital, Tokyo 113-8655, Japan.
Masahiro WatanabeCenter for Preventive Medical Sciences, Chiba University, Chiba 263-8522, Japan.
Shingo OchiaiDepartment of Bioenvironmental Medicine, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Hiroshi OhnoLaboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa 230-0045, Japan.
Hideoki FukuokaCenter for Preventive Medical Sciences, Chiba University, Chiba 263-8522, Japan.
Naoki ShimojoCenter for Preventive Medical Sciences, Chiba University, Chiba 263-8522, Japan.
Chisato MoriCenter for Preventive Medical Sciences, Chiba University, Chiba 263-8522, Japan.
Chiba University · JPRIKEN Center for Integrative Medical Sciences · JPChiba University Hospital · JPFukushima Medical University · JPJapanese Red Cross College of Nursing · JPUniversity of Tokyo Hospital · JP

Funding

Chiba Foundation for Health Promotion & Disease Prevention no numberJapan Society for the Promotion of Science 16H01781
6 · The paper itself

Abstract

Chemokine (C-C motif) ligand 17 (CCL17) is a pro-allergic factor: high CCL17 levels in cord blood (CB) precede later allergic predisposition. Short-chain fatty acid (SCFA) treatment during pregnancy has been shown to protect mouse pups against allergic diseases. The maternal microbial metabolome during pregnancy may affect fetal allergic immune responses. We therefore examined the associations between CB CCL17 and gut SCFA levels in healthy pregnant Japanese women. CB CCL17 serum levels at birth, and maternal non-specific IgE levels in maternal sera at 32 weeks of gestation were measured. Maternal stool samples were collected at 12 (

Indexed as

AdultBiomarkersChemokine CCL17Fatty Acids, VolatileFecesFemaleFetal BloodGastrointestinal MicrobiomeHumansInfant, NewbornMaleMetabolomePregnancyBiomarkersCCL17 protein, humanChemokine CCL17Fatty Acids, VolatileCCL17/TARCcord bloodmaternal gut microbiotashort-chain fatty acids

Identifiers

PMID34444997
PMCPMC8398127
OpenAlexW3196237384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.