Evidence map›Paper›PMID 34444977›Full record

ArticleNutrients2021

Soy Consumption, but Not Dairy Consumption, Is Inversely Associated with Fatty Acid Desaturase Activity in Young Adults.

Melissa Gonzalez-Soto, Salma A Abdelmagid, David W L Ma, Ahmed El-Sohemy, David M Mutch

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05820256 (Investigating the Effects of Milk Protein Versus Soy Protein on Essential Omega-3 Fatty Acid Metabolism), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05820256 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Investigating the Effects of Milk Protein Versus Soy Protein on Essential Omega-3 Fatty Acid Metabolism: A Randomized Parallel-arm Human Trial in Healthy Canadian Adults

TypeinterventionalSponsorUniversity of GuelphRan2023 to 2025Enrolled32ConditionsNutrition, HealthyArmsMilk Protein Isolate (MPI), Soy Protein Isolate (SPI)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Comparing Soy and Milk Protein Regulation of Hepatic Omega-3 Fatty Acid Biosynthesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Melissa Gonzalez-SotoDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0003-4309-5604
Salma A AbdelmagidDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
David W L MaDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0002-1165-5972
Ahmed El-SohemyDepartment of Nutritional Sciences, University of Toronto, Toronto, ON M5S 1A8, Canada.
David M MutchDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0002-0908-7259
University of Guelph · CAUniversity of Toronto · CA

Funding

Dairy Farmers of Canada N/A
6 · The paper itself

Abstract

Past research using hepatic rat microsomes showed that soy protein suppressed delta-6 desaturase activity (D6D) compared to casein (a dairy protein). The effects of soy and dairy on desaturase pathway activity in humans remain poorly investigated. The objective of this analysis was to investigate the association between soy and dairy consumption with plasma fatty acids and estimate the desaturase pathway activity in a multiethnic Canadian population of young adults. We analyzed data from men (

Indexed as

Dairy ProductsDietFeeding BehaviorSoy FoodsAnimalsCanadaCaseinsFatty Acid DesaturasesFatty Acids, Omega-6FemaleGlycine maxHumansMaleMilkOntarioSoybean ProteinsCaseinsFADS2 protein, humanFatty Acid DesaturasesFatty Acids, Omega-6Soybean Proteinsdairydelta-6 desaturasefluid milkhumansLC-PUFAplant-based beveragesoy beverage

Identifiers

PMID34444977
PMCPMC8400722
OpenAlexW3194174708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.