Evidence map›Paper›PMID 34444949›Full record

Trial reportNutrients2021

Clinical Outcomes after Oat Beta-Glucans Dietary Treatment in Gastritis Patients.

Sylwia Gudej, Rafał Filip, Joanna Harasym, Jacek Wilczak, Katarzyna Dziendzikowska, Michał Oczkowski, Małgorzata Jałosińska, Małgorzata Juszczak, Ewa Lange, Joanna Gromadzka-Ostrowska

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  9. Trained Immunity and Trained Tolerance: The Case ofInternational journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sylwia GudejDepartment of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (SGGW-WULS), Nowoursynowska 159c, 02-776 Warsaw, Poland.
Rafał FilipDepartment of Gastroenterology with IBD Unit, Faculty of Medicine, University of Rzeszow, Kopisto 2A Str., 35-315 Rzeszow, Poland.ORCID 0000-0002-5954-151X
Joanna HarasymAdaptive Food Systems Accelerator-Research Centre, Wroclaw University of Economics and Business, Komandorska 118/120, 53-345 Wrocław, Poland.ORCID 0000-0003-0806-7106
Jacek WilczakDepartment of Physiological Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences (SGGW-WULS), Nowoursynowska 159, 02-776 Warsaw, Poland.
Katarzyna DziendzikowskaDepartment of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (SGGW-WULS), Nowoursynowska 159c, 02-776 Warsaw, Poland.ORCID 0000-0002-8069-6356
Michał OczkowskiDepartment of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (SGGW-WULS), Nowoursynowska 159c, 02-776 Warsaw, Poland.ORCID 0000-0002-5999-5140
Małgorzata JałosińskaDepartment of Food Gastronomy and Food Hygiene, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (SGGW-WULS), Nowoursynowska 159c, 02-776 Warsaw, Poland.
Małgorzata JuszczakDepartment of Medical Biology, Institute of Rural Health, Jaczewskiego 2, 20-090 Lublin, Poland.
Ewa LangeDepartment of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (SGGW-WULS), Nowoursynowska 159c, 02-776 Warsaw, Poland.ORCID 0000-0003-1093-4571
Joanna Gromadzka-OstrowskaDepartment of Dietetics, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (SGGW-WULS), Nowoursynowska 159c, 02-776 Warsaw, Poland.ORCID 0000-0002-9529-3744
Warsaw University of Life Sciences · PLInstytut Medycyny Wsi im. Witolda Chodźki · PLUniversity of Rzeszów · PLWroclaw University of Economics and Business · PL

Funding

Narodowe Centrum Nauki NN312 427440
6 · The paper itself

Abstract

The prevalence of gastritis in humans is constantly growing and a prediction of an increase in this health problem is observed in many countries. For this reason, effective dietary therapies are sought that can alleviate the course of this disease. The objective of this study was to determine the effect of chemically pure oat beta-glucan preparations with different molar masses, low or high, used for 30 days in patients with histologically diagnosed chronic gastritis. The study enrolled 48 people of both genders of different ages recruited from 129 patients with a gastritis diagnosis. Before and after the therapy, hematological, biochemical, immunological and redox balance parameters were determined in the blood and the number of lactic acid bacteria and SCFA concentrations in the feces. Our results demonstrated a beneficial effect of oat beta-glucans with high molar mass in chronic gastritis in humans, resulting in reduced mucosal damage and healthy changes in SCFA fecal concentration and peripheral blood serum glutathione metabolism and antioxidant defense parameters. This fraction of a highly purified oat beta-glucan is safe for humans. Its action is effective after 30 days of use, which sheds new light on the nutritional treatment of chronic gastritis.

Indexed as

AvenaAdultAgedbeta-GlucansChronic DiseaseDouble-Blind MethodFatty Acids, VolatileFecesFemaleGastritisHumansLactobacillalesMaleMiddle AgedOsmolar ConcentrationTreatment Outcomebeta-GlucansFatty Acids, Volatileantioxidant propertiesgastritisinflammatory processoat beta-glucanprebioticsshort-chain fatty acids

Identifiers

PMID34444949
PMCPMC8400320
OpenAlexW3196084106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.