Evidence map›Paper›PMID 34444940›Full record

Trial reportNutrients2021

Metabolic, Affective and Neurocognitive Characterization of Metabolic Syndrome Patients with and without Food Addiction. Implications for Weight Progression.

Lucía Camacho-Barcia, Lucero Munguía, Ignacio Lucas, Rafael de la Torre, Jordi Salas-Salvadó, Xavier Pintó, Dolores Corella, Roser Granero, Susana Jiménez-Murcia, Inmaculada González-Monje and 6 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Food Addiction in Individuals With Overweight and Obesity Undergoing a 12-Week Long Tailored mHealth Weight Loss Intervention.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Trial
  3. Review
  4. Article
  5. Environmental Influences on Food Addiction and Cardiometabolic Profiles in Law Enforcement Officers.International journal of environmental research and public health · 2026
    Article
  6. Article
  7. Food Addiction Is Strongly Associated With Psychopathology and Reduced Psychological Well-Being Among Adults Irrespective of BMI.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Lucía Camacho-BarciaDepartment of Psychiatry, University Hospital of Bellvitge-IDIBELL, Hospitalet de Llobregat, 08907 Barcelona, Spain.ORCID 0000-0002-5989-936X
Lucero MunguíaDepartment of Psychiatry, University Hospital of Bellvitge-IDIBELL, Hospitalet de Llobregat, 08907 Barcelona, Spain.ORCID 0000-0002-9751-810X
Ignacio LucasDepartment of Psychiatry, University Hospital of Bellvitge-IDIBELL, Hospitalet de Llobregat, 08907 Barcelona, Spain.ORCID 0000-0001-9426-5082
Rafael de la TorreCIBER Physiology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain.ORCID 0000-0002-6765-1866
Jordi Salas-SalvadóCIBER Physiology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain.ORCID 0000-0003-2700-7459
Xavier PintóCIBER Physiology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain.ORCID 0000-0002-2216-2444
Dolores CorellaCIBER Physiology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain.ORCID 0000-0002-2366-4104
Roser GraneroCIBER Physiology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain.ORCID 0000-0001-6308-3198
Susana Jiménez-MurciaDepartment of Psychiatry, University Hospital of Bellvitge-IDIBELL, Hospitalet de Llobregat, 08907 Barcelona, Spain.ORCID 0000-0002-3596-8033
Inmaculada González-MonjeCIBER Physiology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain.
Virginia Esteve-LuqueLipids and Vascular Risk Unit, Internal Medicine, University Hospital of Bellvitge-IDIBELL, Hospitalet de Llobregat, 08907 Barcelona, Spain.ORCID 0000-0002-7631-8301
Aida Cuenca-RoyoCIBER Physiology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain.
Carlos Gómez-MartínezCIBER Physiology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain.
Indira Paz-GranielCIBER Physiology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain.
Laura ForcanoCIBER Physiology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain.
Fernando Fernández-ArandaDepartment of Psychiatry, University Hospital of Bellvitge-IDIBELL, Hospitalet de Llobregat, 08907 Barcelona, Spain.ORCID 0000-0002-2968-9898
Instituto de Salud Carlos III · ESBellvitge University Hospital · ESUniversitat de València · ESUniversitat Autònoma de Barcelona · ESUniversitat Pompeu Fabra · ES

Funding

CERCA Programme/Generalitat de Catalunya SLT006/17/00246Consejería de Salud de la Junta de Andalucía PI0458/2013, PS0358/2016, PI0137/2018EU-H2020 Eat2beNICE/ H2020-SFS-2016-2 Ref 728018; PRIME/ H2020-SC1-BHC-2018-2020; Ref: 847879Generalitat Valenciana PROMETEO/2017/017Instituto de Salud Carlos III PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI1
6 · The paper itself

Abstract

According to the food addiction (FA) model, the consumption of certain types of food could be potentially addictive and can lead to changes in intake regulation. We aimed to describe metabolic parameters, dietary characteristics, and affective and neurocognitive vulnerabilities of individuals with and without FA, and to explore its influences on weight loss progression. The sample included 448 adults (55-75 years) with overweight/obesity and metabolic syndrome from the PREDIMED-Plus cognition sub-study. Cognitive and psychopathological assessments, as well as dietary, biochemical, and metabolic measurements, were assessed at baseline. Weight progression was evaluated after a 3-year follow up. The presence of FA was associated with higher depressive symptomatology, neurocognitive decline, low quality of life, high body mass index (BMI), and high waist circumference, but not with metabolic comorbidities. No differences were observed in the dietary characteristics except for the saturated and monounsaturated fatty acids consumption. After three years, the presence of FA at baseline resulted in a significantly higher weight regain. FA is associated with worse psychological and neurocognitive state and higher weight regain in adults with metabolic syndrome. This condition could be an indicator of bad prognosis in the search for a successful weight loss process.

Indexed as

AgedBody Mass IndexCardiovascular DiseasesCognitionDepressionDietFatty AcidsFatty Acids, MonounsaturatedFemaleFood AddictionHumansMaleMetabolic SyndromeMiddle AgedObesityOverweightFatty AcidsFatty Acids, Monounsaturateddepressionfood addictionmetabolic syndromeneurocognitive statequality of life

Identifiers

PMID34444940
PMCPMC8398101
OpenAlexW3194031663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.