Evidence map›Paper›PMID 34444919›Full record

ArticleNutrients2021

In Vivo and In Vitro Antidiabetic and Anti-Inflammatory Properties of Flax (

Hamza Mechchate, Imane Es-Safi, Raffaele Conte, Christophe Hano, Amal Amaghnouje, Fatima Zahra Jawhari, Nabil Radouane, Noureddine Bencheikh, Andriy Grafov, Dalila Bousta

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  5. Pharmacological and Pharmacokinetic Profiling ofFood science & nutrition · 2026
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  6. Bioactive fractions ofMetabolism open · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Hamza MechchateLaboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, Morocco.ORCID 0000-0003-4571-9089
Imane Es-SafiLaboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, Morocco.ORCID 0000-0002-9239-3045
Raffaele ConteResearch Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-6266-4991
Christophe HanoLaboratoire de Biologie des Ligneux et des Grandes Cultures, INRAE USC1328, Campus Eure et Loir, Orleans University, 45067 Orleans, France.ORCID 0000-0001-9938-0151
Amal AmaghnoujeLaboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, Morocco.ORCID 0000-0002-4759-3312
Fatima Zahra JawhariLaboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, Morocco.ORCID 0000-0003-1622-4490
Nabil RadouaneLaboratory of Functional Ecology and Environmental Engineering, Sidi Mohamed Ben Abdellah University, P.O. Box 2202, Fez 30000, Morocco.ORCID 0000-0002-1173-470X
Noureddine BencheikhLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Oujda 60000, Morocco.ORCID 0000-0002-4581-2470
Andriy GrafovLaboratory of Inorganic Chemistry, Department of Chemistry, University of Helsinki, P.O. Box 55, FI-00014 Helsinki, Finland.ORCID 0000-0002-7387-3676
Dalila BoustaLaboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, Morocco.
Sidi Mohamed Ben Abdellah University · MAUniversity of Helsinki · FIInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRMohamed I University · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flaxseed is an oilseed (45-50% oil on a dry-weight basis) crop. Its oil has demonstrated multiple health benefits and industrial applications. The goal of this research was to evaluate the antidiabetic and anti-inflammatory potential of the free polyphenol fraction of flax (

Indexed as

AnimalsAnti-Inflammatory AgentsBlood GlucoseBody WeightDiabetes Mellitus, ExperimentalDietary SupplementsFlaxHumansHypoglycemic AgentsMicePlant OilsPolyphenolsRatsRats, WistarSeedsAnti-Inflammatory AgentsBlood GlucoseHypoglycemic AgentsPlant OilsPolyphenolsantidiabeticanti-inflammatorycarrageenan-induced edemadiabetes mellitusdyslipidemiaflaxflaxseedhemolysis testLC-MS/MSpolyphenols extraction

Identifiers

PMID34444919
PMCPMC8398359
OpenAlexW3192858133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.