Evidence map›Paper›PMID 34444917›Full record

Observational studyNutrients2021

Risk of Malnutrition upon Admission and after Discharge in Acutely Admitted Older Medical Patients: A Prospective Observational Study.

Aino Leegaard Andersen, Rikke Lundsgaard Nielsen, Morten Baltzer Houlind, Juliette Tavenier, Line J H Rasmussen, Lillian Mørch Jørgensen, Charlotte Treldal, Anne Marie Beck, Mette Merete Pedersen, Ove Andersen and 1 more

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07367412 (Effect of Zinc Supplementation on Occurrence of Infections in Older Medical Patients), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07367412 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Zinc Supplementation on Occurrence of Infections in Older Medical Patients (ZOOM) - a Cluster Randomized Controlled Trial (ZOOM OUT).

TypeinterventionalSponsorHerlev HospitalRan2026 to 2028Enrolled8,000ConditionsOlder Adults (65 Years and Older), Medical Patients in the Emergency DepartmentArmsZinc (zinc sulphate)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Effects of SativexNutrients · 2026
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Aino Leegaard AndersenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegård Alle 30, 2650 Hvidovre, Denmark.ORCID 0000-0003-1449-1931
Rikke Lundsgaard NielsenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegård Alle 30, 2650 Hvidovre, Denmark.ORCID 0000-0003-2208-7349
Morten Baltzer HoulindDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegård Alle 30, 2650 Hvidovre, Denmark.ORCID 0000-0003-4058-3012
Juliette TavenierDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegård Alle 30, 2650 Hvidovre, Denmark.
Line J H RasmussenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegård Alle 30, 2650 Hvidovre, Denmark.ORCID 0000-0001-6613-2469
Lillian Mørch JørgensenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegård Alle 30, 2650 Hvidovre, Denmark.
Charlotte TreldalDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegård Alle 30, 2650 Hvidovre, Denmark.
Anne Marie BeckDepartment of Nursing and Nutrition, University College Copenhagen, Sigurdsgade 26, 2200 Copenhagen N, Denmark.
Mette Merete PedersenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegård Alle 30, 2650 Hvidovre, Denmark.ORCID 0000-0001-5719-2531
Ove AndersenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegård Alle 30, 2650 Hvidovre, Denmark.
Janne PetersenDepartment of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegård Alle 30, 2650 Hvidovre, Denmark.ORCID 0000-0001-7323-2548
University of Copenhagen · DKHvidovre Hospital · DKDuke University · USGentofte Hospital · DK

Funding

Department of Clinical Research, Copenhagen University Hospital, Hvidovre, Denmark NADoctor Sofus Carl Emil Friis and wife Olga Doris Friis' scolarship NAKøbenhavns Universitet NALundbeckfonden R180-2014-3360Lundbeckfonden R288-2018-380The Capital Region of Denmark NAThe Capital Region Pharmacy NAThe Toyota Foundation NA
6 · The paper itself

Abstract

There is a lack of knowledge about malnutrition and risk of malnutrition upon admission and after discharge in older medical patients. This study aimed to describe prevalence, risk factors, and screening tools for malnutrition in older medical patients. In a prospective observational study, malnutrition was evaluated in 128 older medical patients (≥65 years) using the Nutritional Risk Screening 2002 (NRS-2002), the Mini Nutritional Assessment-Short Form (MNA-SF) and the Eating Validation Scheme (EVS). The European Society of Clinical Nutrition (ESPEN) diagnostic criteria from 2015 were applied for diagnosis. Agreement between the screening tools was evaluated by kappa statistics. Risk factors for malnutrition included polypharmacy, dysphagia, depression, low functional capacity, eating-related problems and lowered cognitive function. Malnutrition or risk of malnutrition were prevalent at baseline (59-98%) and follow-up (30-88%). The baseline, follow-up and transitional agreements ranged from slight to moderate. NRS-2002 and MNA-SF yielded the highest agreement (kappa: 0.31 (95% Confidence Interval (CI) 0.18-0.44) to 0.57 (95%CI 0.42-0.72)). Prevalence of risk factors ranged from 17-68%. Applying ESPEN 2015 diagnostic criteria, 15% had malnutrition at baseline and 13% at follow-up. In conclusion, malnutrition, risk of malnutrition and risk factors hereof are prevalent in older medical patients. MNA-SF and NRS-2002 showed the highest agreement at baseline, follow-up, and transitionally.

Indexed as

AgedAged, 80 and overFemaleGeriatric AssessmentHumansMaleMalnutritionMass ScreeningNutritional StatusNutrition AssessmentPatient AdmissionPatient DischargePrevalenceProspective StudiesReproducibility of ResultsRisk Assessmentemergency servicegeriatricshospitalmalnutritionnutritional assessmentrisk factors for malnutrition

Identifiers

PMID34444917
PMCPMC8398199
OpenAlexW3189897690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.