Evidence map›Paper›PMID 34444865›Full record

ArticleNutrients2021

Faecal Microbiota Composition Varies between Patients with Breast Cancer and Healthy Women: A Comparative Case-Control Study.

Christine Bobin-Dubigeon, Huyen Trang Luu, Sébastien Leuillet, Sidonie N Lavergne, Thomas Carton, Françoise Le Vacon, Catherine Michel, Hassane Nazih, Jean-Marie Bard

Abstract readComparative Study
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Changes in the fecal microbiota of breast cancer patients based on 16S rRNA gene sequencing: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Pooled it
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. The dialogue between breast cancer and microorganisms.Frontiers in cellular and infection microbiology · 2026
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Investigating the role of inflammatory cytokines in mediating the effect of gut microbiota on gastrointestinal cancers: a mendelian randomization study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christine Bobin-DubigeonInstitut de Cancérologie de l'Ouest, 44805 Saint-Herblain, France.ORCID 0000-0001-8944-3219
Huyen Trang LuuEA 2160-IUML FR3473 CNRS, Nantes University, 44035 Nantes, France.
Sébastien LeuilletBiofortis Mérieux NutriSciences, 3 Route de la Chatterie, 44800 Saint-Herblain, France.
Sidonie N LavergneBiofortis Mérieux NutriSciences, 3 Route de la Chatterie, 44800 Saint-Herblain, France.
Thomas CartonBiofortis Mérieux NutriSciences, 3 Route de la Chatterie, 44800 Saint-Herblain, France.
Françoise Le VaconBiofortis Mérieux NutriSciences, 3 Route de la Chatterie, 44800 Saint-Herblain, France.
Catherine MichelResearch Center of Human Nutrition CRNH Ouest, 44093 Nantes, France.
Hassane NazihEA 2160-IUML FR3473 CNRS, Nantes University, 44035 Nantes, France.ORCID 0000-0002-3607-295X
Jean-Marie BardInstitut de Cancérologie de l'Ouest, 44805 Saint-Herblain, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal microbiota plays an essential role in many diseases, such as obesity, irritable bowel disease (IBD), and cancer. This study aimed to characterize the faecal microbiota from early-stage breast cancer (BC) patients and healthy controls. Faeces from newly diagnosed breast cancer patients, mainly for an invasive carcinoma of no specific type (HR

Indexed as

AgedBreast NeoplasmsCase-Control StudiesFecesFemaleGastrointestinal MicrobiomeHumansMiddle AgedReal-Time Polymerase Chain ReactionRNA, Ribosomal, 16SSequence Analysis, RNARNA, Ribosomal, 16S16S rRNAabundancebreast cancerhealthy womenmetabarcoding analysesmicrobiotaqPCR

Identifiers

PMID34444865
PMCPMC8399700

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.