Evidence map›Paper›PMID 34444857›Full record

ArticleNutrients2021

Elucidation of Melanogenesis-Associated Signaling Pathways Regulated by Argan Press Cake in B16 Melanoma Cells.

Thouria Bourhim, Myra O Villareal, Chemseddoha Gadhi, Hiroko Isoda

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Frontiers in bioengineering and biotechnology · 2024
    Article
  2. Article
  3. Review
  4. Argan (International journal of molecular sciences · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Thouria BourhimFaculty of Sciences Semlalia, Cadi Ayyad University, Avenue Prince Moulay Abdellah, B.P. 2390, Marrakesh 40000, Morocco.ORCID 0000-0003-0319-6427
Myra O VillarealAlliance for Research on the Mediterranean and North Africa (ARENA), University of Tsukuba, Tennodai 1-1-1, Tsukuba 305-8572, Japan.ORCID 0000-0003-4338-3323
Chemseddoha GadhiFaculty of Sciences Semlalia, Cadi Ayyad University, Avenue Prince Moulay Abdellah, B.P. 2390, Marrakesh 40000, Morocco.ORCID 0000-0003-4524-5362
Hiroko IsodaAlliance for Research on the Mediterranean and North Africa (ARENA), University of Tsukuba, Tennodai 1-1-1, Tsukuba 305-8572, Japan.
Cadi Ayyad University · MAUniversity of Tsukuba · JP

Funding

JICA-JST SATREPS Project
6 · The paper itself

Abstract

The beneficial effect on health of argan oil is recognized worldwide. We have previously reported that the cake that remains after argan oil extraction (argan press-cake or APC) inhibits melanogenesis in B16 melanoma cells in a time-dependent manner without cytotoxicity. In this study, the global gene expression profile of B16 melanoma cells treated with APC extract was determined in order to gain an understanding of the possible mechanisms of action of APC. The results suggest that APC extract inhibits melanin biosynthesis by down-regulating microphthalmia-associated transcription factor (

Indexed as

SapotaceaeAnimalsDermatologic AgentsDown-RegulationMelanoma, ExperimentalMelanosomesMiceMicrophthalmia-Associated Transcription FactorPlant Extractsrab27 GTP-Binding ProteinsSignal TransductionSkin NeoplasmsDermatologic AgentsMicrophthalmia-Associated Transcription FactorPlant Extractsrab27 GTP-Binding Proteinsargan press-cakecAMP/PKAJNKmicroarray analysisMITFWnt/β-catenin

Identifiers

PMID34444857
PMCPMC8398289
OpenAlexW3191357607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.