Evidence map›Paper›PMID 34444838›Full record

Trial reportNutrients2021

Randomized Trial on the Effects of Dietary Potassium on Blood Pressure and Serum Potassium Levels in Adults with Chronic Kidney Disease.

Sharon Turban, Stephen P Juraschek, Edgar R Miller, Cheryl A M Anderson, Karen White, Jeanne Charleston, Lawrence J Appel

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07494266 (Säkerheten av en hälsosam växtbaserad Kost Med högre kaliuminnerhåll, jämfört Med en hälsosam växtbaserad Kost Med begränsat kaliuminnehåll Hos Patienter Med Kronisk Njursjukdom), which is not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07494266 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Säkerheten av en hälsosam växtbaserad Kost Med högre kaliuminnerhåll, jämfört Med en hälsosam växtbaserad Kost Med begränsat kaliuminnehåll Hos Patienter Med Kronisk Njursjukdom: En Pilotstudie

TypeinterventionalSponsorKarolinska InstitutetRan2026 to 2030Enrolled30ConditionsHyperkalemia, Chronic Kidney Disease (Stages 4 and 5)ArmsHealthy plant-based diet (healthy-PBD), Potassium-restricted plant-based diet
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. Environmental Drivers ofFood science & nutrition · 2026
    Article
  3. Potassium and the kidney.Nature reviews. Nephrology · 2026
    Review
  4. How Does Dietary Potassium Influence BP?Journal of the American Society of Nephrology : JASN · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Revisiting resistant hypertension in kidney disease.Current opinion in nephrology and hypertension · 2024
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. New Insights Into Dietary Approaches to Potassium Management in Chronic Kidney Disease.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2023
    Review
  17. Article
  18. Potassium.Advances in nutrition (Bethesda, Md.) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sharon TurbanSchool of Medicine, Johns Hopkins University, Baltimore, MD 21087, USA.
Stephen P JuraschekBeth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Edgar R MillerSchool of Medicine, Johns Hopkins University, Baltimore, MD 21087, USA.
Cheryl A M AndersonHerbert Wertheim School of Public Health and Human Longevity Science, University of California at San Diego, San Diego, CA 92093, USA.
Karen WhiteSchool of Medicine, Johns Hopkins University, Baltimore, MD 21087, USA.
Jeanne CharlestonBloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21087, USA.
Lawrence J AppelSchool of Medicine, Johns Hopkins University, Baltimore, MD 21087, USA.ORCID 0000-0002-0673-6823
Johns Hopkins University · USBeth Israel Deaconess Medical Center · USHuman Longevity (United States) · US

Funding

American Heart Association 0835162NNIH HHS NIH/NHLBI 7K23HL135273-02
6 · The paper itself

Abstract

In the general population, an increased potassium (K) intake lowers blood pressure (BP). The effects of K have not been well-studied in individuals with chronic kidney disease (CKD). This randomized feeding trial with a 2-period crossover design compared the effects of diets containing 100 and 40 mmol K/day on BP in 29 adults with stage 3 CKD and treated or untreated systolic BP (SBP) 120-159 mmHg and diastolic BP (DBP) <100 mmHg. The primary outcome was 24 h ambulatory systolic BP. The higher-versus lower-K diet had no significant effect on 24 h SBP (-2.12 mm Hg;

Indexed as

AgedBlood PressureFemaleHumansHyperkalemiaHypertensionMaleMiddle AgedPotassiumPotassium, DietaryRenal Insufficiency, ChronicPotassiumPotassium, Dietaryblood pressurechronic kidney diseasehyperkalemiahypertensionpotassium

Identifiers

PMID34444838
PMCPMC8398615
OpenAlexW3188984020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.