Evidence map›Paper›PMID 34444806›Full record

Observational studyNutrients2021

CT-Determined Sarcopenia in GLIM-Defined Malnutrition and Prediction of 6-Month Mortality in Cancer Inpatients.

Francisco José Sánchez-Torralvo, Ignacio Ruiz-García, Victoria Contreras-Bolívar, Inmaculada González-Almendros, María Ruiz-Vico, Jose Abuín-Fernández, Manuel Barrios, Emilio Alba, Gabriel Olveira

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

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  9. The Influence of Muscle Morphology on Oncological Outcomes: A Review.Journal of frailty, sarcopenia and falls · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Francisco José Sánchez-TorralvoUnidad de Gestión Clínica de Endocrinología y Nutrición, IBIMA, Hospital Regional Universitario de Málaga, Universidad de Málaga, 29007 Málaga, Spain.ORCID 0000-0002-0739-2567
Ignacio Ruiz-GarcíaUnidad de Gestión Clínica de Endocrinología y Nutrición, IBIMA, Hospital Regional Universitario de Málaga, Universidad de Málaga, 29007 Málaga, Spain.
Victoria Contreras-BolívarUGG Endocrinology and Nutrition at the University Hospital San Cecilio, 18000 Granada, Spain.
Inmaculada González-AlmendrosUnidad de Gestión Clínica de Radiodiagnóstico, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.
María Ruiz-VicoUnidad de Gestión Clínica de Oncología Médica, Hospital Regional Universitario de Málaga, Universidad de Málaga, 29010 Málaga, Spain.ORCID 0000-0002-5638-0634
Jose Abuín-FernándezUnidad de Gestión Clínica de Endocrinología y Nutrición, IBIMA, Hospital Regional Universitario de Málaga, Universidad de Málaga, 29007 Málaga, Spain.
Manuel BarriosUnidad de Gestión Clínica de Hematología y Hemoterapia, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.
Emilio AlbaUnidad de Gestión Clínica de Oncología Médica, Hospital Regional Universitario de Málaga, Universidad de Málaga, 29010 Málaga, Spain.
Gabriel OlveiraUnidad de Gestión Clínica de Endocrinología y Nutrición, IBIMA, Hospital Regional Universitario de Málaga, Universidad de Málaga, 29007 Málaga, Spain.
Hospital Regional Universitario de Málaga · ESInstituto de Investigación Biosanitaria de Granada · ES

Funding

Abbott Nutrition unrestricted grantInstituto de Salud Carlos III Río Hortega Grant CM20/00225
6 · The paper itself

Abstract

Our objective was to evaluate the clinical application of third lumbar vertebra (L3)-computer tomography (CT)-determined sarcopenia as a marker of muscle mass in cancer inpatients diagnosed with malnutrition according to the Global Leadership Initiative on Malnutrition (GLIM) criteria and to establish its association with 6-month mortality.

methodsThis was an observational, prospective study in patients from an inpatient oncology unit. We performed a nutritional assessment according to GLIM criteria, including muscle cross-sectional area at L3 by CT and skeletal muscle index (SMI). Six-month mortality was evaluated.

resultsA total of 208 patients were included. The skeletal muscle cross-sectional area at L3 was 136.2 ± 32.5 cm

conclusionsLow muscle mass, assessed by L3-CT, was observed to affect more than half of cancer inpatients. The deceased patients at 6 months had a lower skeletal muscle cross-sectional area and SMI. Malnutrition according to GLIM criteria using CT-determined sarcopenia was shown to adequately predict 6-month mortality.

Indexed as

Tomography, X-Ray ComputedAgedBody CompositionFemaleHumansInpatientsLeadershipMaleMalnutritionMiddle AgedMuscle, SkeletalNeoplasmsNutritional StatusNutrition AssessmentProspective StudiesSarcopeniabody compositioncomputed tomographyGLIM criteriamalnutritiononcology

Identifiers

PMID34444806
PMCPMC8398807
OpenAlexW3190665802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.