Evidence map›Paper›PMID 34444730›Full record

ArticleNutrients2021

Hair EDX Analysis-A Promising Tool for Micronutrient Status Evaluation of Patients with IBD?

Georgiana-Emmanuela Gîlcă-Blanariu, Adina Coroabă, Manuela Ciocoiu, Anca Trifan, Gabriel Dimofte, Smaranda Diaconescu, Vlad-Adrian Afrăsânie, Gheorghe G Balan, Tudor Pinteală, Gabriela Ștefănescu

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Georgiana-Emmanuela Gîlcă-BlanariuFaculty of Medicine, Grigore T Popa University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0000-0002-5590-6462
Adina CoroabăPetru Poni Institute of Macromolecular Chemistry, 700487 Iași, Romania.ORCID 0000-0002-4340-4756
Manuela CiocoiuFaculty of Medicine, Grigore T Popa University of Medicine and Pharmacy, 700115 Iași, Romania.
Anca TrifanFaculty of Medicine, Grigore T Popa University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0000-0001-9144-5520
Gabriel DimofteFaculty of Medicine, Grigore T Popa University of Medicine and Pharmacy, 700115 Iași, Romania.
Smaranda DiaconescuFaculty of Medicine, Grigore T Popa University of Medicine and Pharmacy, 700115 Iași, Romania.
Vlad-Adrian AfrăsânieFaculty of Medicine, Grigore T Popa University of Medicine and Pharmacy, 700115 Iași, Romania.
Gheorghe G BalanFaculty of Medicine, Grigore T Popa University of Medicine and Pharmacy, 700115 Iași, Romania.
Tudor PintealăSf Spiridon County Clinical Emergency Hospital, 700111 Iași, Romania.
Gabriela ȘtefănescuFaculty of Medicine, Grigore T Popa University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0000-0002-1394-8648
Grigore T. Popa University of Medicine and Pharmacy · ROInstitutul de Chimie Macromoleculară Petru PoniSpitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micronutrient deficiencies can arise in various conditions, including inflammatory bowel diseases (IBD), and diagnosing these deficiencies can be challenging in the absence of specific clinical signs. The aim of this study was to evaluate the status of various trace elements hair concentration in IBD patients compared to a healthy control group and to identify potential correlations between the micronutrient status and relevant parameters related to disease activity. The concentrations of iron, magnesium, calcium, zinc, copper, manganese, selenium and sulfur in the hair of 37 IBD patients with prior diagnosed IBD (12 Crohn's disease and 25 ulcerative colitis) and 31 healthy controls were evaluated by Energy Dispersive X-Ray spectroscopy (EDX). Significant differences in hair concentration profile of studied trace elements were identified for IBD patients compared to healthy controls. A significantly decreased hair concentration of iron, magnesium, calcium and selenium and a significantly increased sulfur hair concentration were observed in IBD patients at the time of evaluation. A decreased hair calcium concentration (

Indexed as

AdultCalciumColitis, UlcerativeCopperCrohn DiseaseFemaleHairHumansIronMagnesiumMaleMicronutrientsMiddle AgedNutritional StatusSeleniumSpectrometry, X-Ray EmissionCalciumCopperIronMagnesiumMicronutrientsSeleniumSulfurTrace ElementsZinccalciumcopperEDXinflammatory bowel diseaseironmagnesiummanganesemicronutrientstrace elementzinc

Identifiers

PMID34444730
PMCPMC8399661
OpenAlexW3185785156

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.