Evidence map›Paper›PMID 34444687›Full record

ArticleNutrients2021

Development and Validation of a Predictive Model of Hypovitaminosis D in General Adult Population: SCOPYD Study.

Marie Viprey, Blandine Merle, Benjamin Riche, Julie Freyssenge, Pascal Rippert, Mohammed-Amine Chakir, Thierry Thomas, Sandrine Malochet-Guinamand, Bernard Cortet, Véronique Breuil and 8 more

Registry-linked trialOpen access · goldAbstract readValidation Study
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02822651 (SCOPYD Study), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02822651 nacompletednot on this map

SCOPYD Study: Development of a Predictive Clinical Score of Hypovitaminosis D

TypeinterventionalSponsorHospices Civils de LyonRan2016 to 2017Enrolled2,592ConditionsVitamin D StatusArmsBlood sampling, self-administered questionnaire
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 1 country.

Marie VipreyResearch on Healthcare Performance RESHAPE, INSERM U1290, Université Claude Bernard Lyon 1, 69003 Lyon, France.ORCID 0000-0002-3281-1970
Blandine MerleINSERM UMR 1033, Université de Lyon, 69000 Lyon, France.
Benjamin RicheUniversité Lyon 1, Université de Lyon, 69000 Lyon, France.
Julie FreyssengeResearch on Healthcare Performance RESHAPE, INSERM U1290, Université Claude Bernard Lyon 1, 69003 Lyon, France.
Pascal RippertHospices Civils de Lyon, Pôle de Sante Publique, 69003 Lyon, France.ORCID 0000-0003-0185-0659
Mohammed-Amine ChakirHospices Civils de Lyon, Pôle de Sante Publique, 69003 Lyon, France.
Thierry ThomasCHU Saint-Etienne, Hôpital Nord, Service de Rhumatologie, INSERM U1059, Laboratoire de Biologie intégrée du Tissu Osseux, Université de Lyon, 42000 Saint-Etienne, France.
Sandrine Malochet-GuinamandCHU Clermont-Ferrand, Hôpital Gabriel Montpied, Service de Rhumatologie, 63000 Clermont-Ferrand, France.
Bernard CortetCHRU de Lille, Service de Rhumatologie, 59000 Lille, France.ORCID 0000-0001-8912-0452
Véronique BreuilCHU de Nice, Service de Rhumatologie, 06000 Nice, France.ORCID 0000-0003-3027-2739
Roland ChapurlatINSERM UMR 1033, Université de Lyon, 69000 Lyon, France.
Marie-Hélène Lafage ProustCHU Saint-Etienne, Hôpital Nord, Service de Rhumatologie, INSERM U1059, Laboratoire de Biologie intégrée du Tissu Osseux, Université de Lyon, 42000 Saint-Etienne, France.
Marie-Christine CarlierDépartement de Biologie, Centre Hospitalier Lyon-Sud, 69495 Pierre-Bénite, France.
Jean-Baptiste FassierHospices Civils de Lyon, Pôle de Sante Publique, 69003 Lyon, France.
Julie HaesebaertResearch on Healthcare Performance RESHAPE, INSERM U1290, Université Claude Bernard Lyon 1, 69003 Lyon, France.
Pascal CailletCHU de Nantes, Unité de Santé Publique Interventionnelle, 44000 Nantes, France.
Muriel RabilloudUniversité Lyon 1, Université de Lyon, 69000 Lyon, France.
Anne-Marie SchottResearch on Healthcare Performance RESHAPE, INSERM U1290, Université Claude Bernard Lyon 1, 69003 Lyon, France.
Université Claude Bernard Lyon 1 · FRHospices Civils de Lyon · FRCentre Hospitalier Universitaire de Clermont-Ferrand · FRCentre Hospitalier Universitaire de Lille · FRCentre Hospitalier Universitaire de Nantes · FRCentre Hospitalier Universitaire de Nice · FRHôpital Lyon Sud · FR

Funding

Direction Générale de l'offre de Soins PHRC-14-14-005
6 · The paper itself

Abstract

The worldwide global increase in serum 25-hydroxyvitamin D (25(OH)D) measurements has led some countries to restrict reimbursement for certain clinical situations only. Another approach could consist in providing physicians with screening tools in order to better target blood test prescription. The objective of the SCOPYD study was to identify the best combination of predictors of serum VitD concentration among adults aged 18-70 years. Potential risk factors for VitD deficiency were collected using a comprehensive self-administered questionnaire. A multivariable linear regression was used to build a predictive model of serum 25(OH)D concentration. Among 2488 participants, 1080 (43.4%) had VitD deficiency (<50 nmol/L) and 195 (7.8%) had severe deficiency (<25 nmol/L). The final model included sunlight exposure in the preceding week and during the last holidays, month of blood sampling, age, sex, body mass index, skin phototype, employment, smoking, sport practice, latitude, and VitD supplementation in preceding year. The area under the curve was 0.82 (95% CI (0.78; 0.85)) for severe deficiency. The model predicted severe deficiency with a sensitivity of 77.9% (95% CI (69.1; 85.7)) and a specificity of 68.3% (95% CI (64.8; 71.9)). We identified a set of predictors of severe VitD deficiency that are easy to collect in routine that may help to better target patients for serum 25(OH)D concentration determination.

Indexed as

AdolescentAdultAgedBody Mass IndexClimateFemaleHumansMaleMiddle AgedRisk FactorsSeasonsSkinSunlightVitamin DVitamin D Deficiency25-hydroxyvitamin DVitamin Dadulthypovitaminosis Dpredictive modelsevere vitamin D deficiencysun exposure assessmentvitamin D deficiency

Identifiers

PMID34444687
PMCPMC8399126
OpenAlexW3186471109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.