ArticleNutrients2021
Reflection of Dietary Iodine in the 24 h Urinary Iodine Concentration, Serum Iodine and Thyroglobulin as Biomarkers of Iodine Status: A Pilot Study.
Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 21 citations in OpenAlex.
- Response feature analyses for repeated measures behavioral data.Biology open · 2026Article
- Establishment of Thyroid Volume Reference Curves for Children in Xinjiang: An Exploration of Goiter Diagnosis and the Role of Iodine Nutrition.Biological trace element research · 2026Article
- Scalp hair and serum iodine as potential biomarkers for iodine intake and their association with the thyroid function.Journal of the Endocrine Society · 2026Article
- Iodine and Bromine Analysis in Human Urine and Serum by ICP-MS, Tailored for High-Throughput Routine Analysis in Population-Based Studies.Analytica (Basel, Switzerland) · 2026Article
- Effect of iodine nutrition on blood glucose and blood lipid levels in different regions: Based on quantile regression.PloS one · 2026Article
- Iodoquinoline-Biofortified Lettuce as a Safe and Bioavailable Dietary Iodine Source: In Vivo Study in Rats.Nutrients · 2025Article
- Serum thyroglobulin levels are predictive of urinary iodine concentration thresholds for defining population iodine status.The British journal of nutrition · 2025Article
- Neighborhood deprivation and iodine levels influence air pollution effects on maternal thyroid function in early pregnancy.Environmental research · 2025Article
- Trace Mineral Imbalances in Global Health: Challenges, Biomarkers, and the Role of Serum Analysis.Nutrients · 2025Review
- Maternal Serum Iodine Concentrations in Early Pregnancy Exhibited Well Diagnostic Ability for Thyroid Dysfunction, Inverse Associations with Gestational Weight Gain, and Birth Size: Longitudinal Analyses Based on Huizhou Mother-Infant Cohort.Biological trace element research · 2025Observational
- Micro-nutrient sufficiency in mothers and babies: management of deficiencies while avoiding overload during pregnancy.Frontiers in nutrition · 2025Review
- Effects of metabolic and organ function factors on the efficacy of radioactive iodine therapy for hyperthyroidism.Frontiers in endocrinology · 2025Article
- Iodine nutritional status and its associations with thyroid function of pregnant women and neonatal TSH.Frontiers in endocrinology · 2024Article
- A Cohort Study on the Effects of Maternal High Serum Iodine Status During Pregnancy on Infants in Terms of Iodine Status and Intellectual, Motor, and Physical Development.Biological trace element research · 2024Article
- Recent data on iodine intake in Croatian schoolchildren: results of 2014-2019 survey.European journal of clinical nutrition · 2023Article
- Iodotyrosines Are Biomarkers for Preclinical Stages of Iodine-Deficient Hypothyroidism inThyroid : official journal of the American Thyroid Association · 2023Article
- Iodine status and supplementation in pregnancy: an overview of the evidence provided by meta-analyses.Reviews in endocrine & metabolic disorders · 2023Review
- Biomarkers of Micronutrients and Phytonutrients and Their Application in Epidemiological Studies.Nutrients · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe iodine status of the US population is considered adequate, but subpopulations remain at risk for iodine deficiency and a biomarker of individual iodine status has yet to be determined. The purpose of this study was to determine whether a 3 day titration diet, providing known quantities of iodized salt, is reflected in 24 h urinary iodine concentration (UIC), serum iodine, and thyroglobulin (Tg).
methodsA total of 10 participants (31.3 ± 4.0 years, 76.1 ± 6.3 kg) completed three, 3 day iodine titration diets (minimal iodine, US RDA, (United States Recommended Daily Allowance), and 3× RDA). The 24 h UIC, serum iodine, and Tg were measured following each diet. The 24 h UIC and an iodine-specific food frequency questionnaire (FFQ) were completed at baseline.
resultsUIC increased an average of 19.3 μg/L for every gram of iodized salt consumed and was different from minimal to RDA (
conclusionThese results suggest that 24 h UIC and serum iodine may be reflective of individual iodine status and may serve as biomarkers of iodine status.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.