Trial reportNutrients2021
Effects of Protein-Rich Nutritional Composition Supplementation on Sarcopenia Indices and Physical Activity during Resistance Exercise Training in Older Women with Knee Osteoarthritis.
Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Combined effects of strength training, whey protein, and HMB on sarcopenia in older people: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Combined resistance training and amino acid-based supplementation for sarcopenia in older adults: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Pooled it
- Pooled it
- Trial
- Effects of oral oligopeptide preparation and exercise intervention in older people with sarcopenia: a randomized controlled trial.BMC geriatrics · 2024Trial
- Causal relationship between dietary habits and low hand grip strength: A Mendelian randomization study.Medicine · 2026Article
- Reframing Nutraceuticals in Knee Osteoarthritis with Sarcopenia: A Muscle-Joint-Centered Narrative Review.Nutrients · 2026Review
- Review
- Sarcopenia in rheumatic and musculoskeletal diseases: pathophysiology, diagnosis, and management.Rheumatology international · 2025Review
- Research progress on sarcopenia in the musculoskeletal system.Bone research · 2025Review
- Combined Protein, Probiotics, and Exercise Therapy for Sarcopenia: A Comprehensive Review.Cells · 2025Review
- Article
- Relationship Between Sarcopenia, Femoral Cartilage Thickness, and Knee Osteoarthritis: Case-Control Study.International journal of rheumatic diseases · 2025Article
- A longitudinal study of dietary inflammatory index and quality of life in people with osteoarthritis: data from the Osteoarthritis Initiative database.Scientific reports · 2025Article
- How Do Muscle Function and Quality Affect the Progression of KOA? A Narrative Review.Orthopaedic surgery · 2024Review
- Osteoarthritis and sarcopenia-related traits: the cross-sectional study from NHANES 2011-2014 and Mendelian randomization study.Journal of orthopaedic surgery and research · 2023Article
- Review
- Article
- [Research progress on the correlation between sarcopenia and osteoarthritis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Older adults with knee osteoarthritis (KOA) are at high risk of sarcopenia. Protein-rich nutritional composition supplementation (PS) combined with resistance exercise training (RET) improves muscle gains and facilitates physical activity in older adults. However, whether PS augments the effects of RET on muscle mass and PA in patients with KOA remains unclear. Therefore, this study identified the effects of PS on sarcopenic indices and PA in older women with KOA subjected to an RET program. Eligible older women aged 60-85 years and diagnosed as having KOA were randomly assigned to either the experimental group (EG) or the control group (CG). Both groups performed RET twice a week for 12 weeks. The EG received additional PS during this period. Outcome measures included appendicular lean mass index, walking speed, physical activity, and scores on the Western Ontario and McMaster Universities Osteoarthritis Index-WOMAC). All measures were tested at baseline and after intervention. With participant characteristics and baseline scores as covariates, analysis of variance was performed to identify between-group differences in changes in all outcome measures after intervention. Statistical significance was defined as
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.