Evidence map›Paper›PMID 34444642›Full record

ArticleNutrients2021

DNA Damage, n-3 Long-Chain PUFA Levels and Proteomic Profile in Brazilian Children and Adolescents.

Tamiris Trevisan de Barros, Vinicius de Paula Venancio, Lívia Cristina Hernandes, Lusania Maria Greggi Antunes, Elaine Hillesheim, Roberta Garcia Salomão, Mariana Giaretta Mathias, Carolina Almeida Coelho-Landell, Roseli Borges Donegá Toffano, Maria Olimpia Ribeiro do Vale Almada and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Tamiris Trevisan de BarrosDepartment of Pediatrics, Medical School of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.ORCID 0000-0002-1459-2233
Vinicius de Paula VenancioSchool of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.ORCID 0000-0003-3239-6380
Lívia Cristina HernandesSchool of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.
Lusania Maria Greggi AntunesSchool of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.ORCID 0000-0002-3079-4388
Elaine HillesheimDepartment of Pediatrics, Medical School of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.ORCID 0000-0002-2138-3181
Roberta Garcia SalomãoDepartment of Pediatrics, Medical School of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.
Mariana Giaretta MathiasDepartment of Pediatrics, Medical School of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.
Carolina Almeida Coelho-LandellDepartment of Pediatrics, Medical School of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.
Roseli Borges Donegá ToffanoDepartment of Pediatrics, Medical School of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.
Maria Olimpia Ribeiro do Vale AlmadaDepartment of Pediatrics, Medical School of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.
José Simon Camelo-JuniorDepartment of Pediatrics, Medical School of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.
Sofia MocoNestlé Research, Société des Produits Nestlé SA, EPFL Innovation Park, CH1015 Lausanne, Switzerland.ORCID 0000-0001-8170-8876
Ornella CominettiNestlé Research, Société des Produits Nestlé SA, EPFL Innovation Park, CH1015 Lausanne, Switzerland.
Fábio da Veiga UedDepartment of Health Sciences, Medical School of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.ORCID 0000-0003-2184-4977
Jim KaputNestlé Research, Société des Produits Nestlé SA, EPFL Innovation Park, CH1015 Lausanne, Switzerland.ORCID 0000-0001-6147-3491
Jacqueline Pontes MonteiroDepartment of Pediatrics, Medical School of Ribeirao Preto, University of Sao Paulo, Sao Paulo 14049-900, Brazil.ORCID 0000-0001-7141-7776
Universidade de São Paulo · BRNestlé (Switzerland) · CH

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 131224/2015-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2012/20421-8Nestlé Institute of Health Sciences RDHS 000054
6 · The paper itself

Abstract

Fatty acids play a significant role in maintaining cellular and DNA protection and we previously found an inverse relationship between blood levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and DNA damage. The aim of this study was to explore differences in proteomic profiles, for 117 pro-inflammatory proteins, in two previously defined groups of individuals with different DNA damage and EPA and DHA levels. Healthy children and adolescents (

Indexed as

DNA DamageAdolescentBrazilChildClass Ia Phosphatidylinositol 3-KinaseClass I Phosphatidylinositol 3-KinasesCross-Sectional StudiesCyclin CCyclin-Dependent Kinase 8Docosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3FemaleHumansHydrolasesInflammationClass Ia Phosphatidylinositol 3-KinaseClass I Phosphatidylinositol 3-KinasesCyclin CCyclin-Dependent Kinase 8Docosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3HydrolaseskynureninasePIK3CA protein, humanPIK3R1 protein, humanProtein Kinase C betaadolescentschildDNA damagefatty acidsproteomic

Identifiers

PMID34444642
PMCPMC8401971
OpenAlexW3186911366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.