Trial reportInternational journal of environmental research and public health2021
Pain Neuroscience Education Combined with Therapeutic Exercises Provides Added Benefit in the Treatment of Chronic Neck Pain.
Trial report in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of the Effects of Neuroscience-Based Pain Education and Myofascial Induction Technique on Pain and Quality of Life in Patients With Chronic Neck Pain
Effects of Lower Trapezius Strengthening Versus Scapular Mobility Exercise on Pain, Range of Motion and Disability Among Snooker Players in Unilateral Neck Pain
Effects of Pain Neuroscience Education and Therapeutic Exercise on Pain, Catastrophizing, Kinesiophobia and Upper Limb Function in Patients With Non-specific Neck Pain.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Mixed Comparison of Interventions for Kinesiophobia in Individuals With Musculoskeletal Pain: Systematic Review and Network Meta-Analysis.Frontiers in psychology · 2022Pooled it
- Acute effects of aerobic versus combined aerobic and cervical-upper extremity resistance exercise on pressure pain threshold, pain perception, and fatigue in workers exposed to high ergonomic risk with chronic non-specific neck pain: a randomized controlled trial.BMC musculoskeletal disorders · 2026Trial
- Effectiveness of Telerehabilitation Exercise Programme on Disability and Pain in Patients With Chronic Non-Specific Neck Pain: Randomised Controlled Trial Assessor-Blinded.Musculoskeletal care · 2025Trial
- Effects of empowered relief on pain catastrophizing and outcomes post-total knee arthroplasty: A quasi-experimental study.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2026Article
- Multidimensional Analysis of Physical, Psychosocial, and Cognitive Impairment in People with Chronic Neck Pain.Medicina (Kaunas, Lithuania) · 2026Article
- "Learn and Move" Program for the Management of Chronic Musculoskeletal Pain in Primary Care: A Pilot Study.Healthcare (Basel, Switzerland) · 2026Article
- Traditional, Complementary, and Alternative Medicine for Self-Care in Chronic Neck and Shoulder Pain: A Scoping Review.Nursing reports (Pavia, Italy) · 2026Review
- Multidimensional Effects of Manual Therapy Combined with Pain Neuroscience-Based Sensorimotor Retraining in a Patient with Chronic Neck Pain: A Case Study Using fNIRS.Healthcare (Basel, Switzerland) · 2025Article
- Effect of Exercise on Chronic Tension-Type Headache and Chronic Migraine: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Effect of Postural Stabilization Exercises in Combination with Cervical Stabilization Exercises on Craniovertebral Angle, Pain, Disability, and Quality of Life in Patients with Chronic Neck Pain: A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2025Article
- A cross-sectional study on pain neurophysiology knowledge among Spanish primary healthcare professionals.Scientific reports · 2025Article
- What is cancer pain? Investigating attitudes of patients, carers, and health professionals: A cross-sectional survey.Pain practice : the official journal of World Institute of Pain · 2025Article
- Effects of Global Postural Re-Education Versus Specific Therapeutic Exercises on Pain, Head Posture, and Pain-Related Psychosocial Factors in Women with Chronic Nonspecific Neck Pain: A Randomized Clinical Trial.Journal of clinical medicine · 2025Article
- Preoperative Home-Based Multimodal Physiotherapy in Patients Scheduled for a Knee Arthroplasty Who Catastrophize About Their Pain: A Randomized Controlled Trial.Journal of clinical medicine · 2025Article
- Clinical Applications and Potential Mechanism of Cold Acclimation Therapy.Journal of multidisciplinary healthcare · 2025Review
- Effectiveness of Non-Pharmacological Interventions in the Management of Pediatric Chronic Pain: A Systematic Review.Children (Basel, Switzerland) · 2024Review
- The Role of Mindfulness Therapy in the Treatment of Chronic Pain.Current pain and headache reports · 2024Review
- An Evaluation of the Design of Multimedia Patient Education Materials in Musculoskeletal Health Care: Systematic Review.JMIR rehabilitation and assistive technologies · 2024Review
- Rehabilitation to Improve Outcomes after Cervical Spine Surgery: Narrative Review.Journal of clinical medicine · 2024Review
- Specific Neurodynamic Exercises on Pain and Disability in Old Women with Chronic Mechanical Neck Pain: A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic neck pain is common in the adult general population. Although the etiology of chronic neck pain is under debate, it is clear that chronic neck pain is multifactorial, with both physical and psychosocial contributors.
objectiveTo determine whether adding pain neuroscience education (PNE) to therapeutic exercises improved their pain-disability index, pain catastrophizing, fear-avoidance beliefs, and pain self-efficacy in subjects with chronic nonspecific neck pain.
methodsThis study was a three-arm randomized control trial. Seventy-two patients with chronic nonspecific neck pain were allocated to three groups: therapeutic exercises alone (n = 24), combined (therapeutic exercises + PNE; (n = 24), and a control group (n = 24). Each program took place three times a week, lasting for six weeks. The disability index, pain catastrophizing, fear-avoidance beliefs, and pain self-efficacy measured by the Neck Pain and Disability Scale (NPAD), Pain Catastrophizing Scale (PCS), Fear-Avoidance Beliefs Questionnaire (FABQ), and Pain Self-Efficacy Questionnaire (PSEQ), respectively. Participants were assessed before and after the six-week intervention, and there was no further follow-up.
resultsFor the outcomes NPAD, PSC, and FABQ, combined intervention demonstrated more significant improvements than therapeutic exercises alone (
conclusionTherapeutic exercises combined with pain neuroscience education reduced the pain-disability index, pain catastrophizing, and fear-avoidance beliefs more than therapeutic exercises alone in patients with chronic neck pain. For pain self-efficacy, there was no statistically significant difference between the two intervention groups; however, the combined group had a more significant effect than therapeutic exercises alone. Further studies with longer periods and follow-up are required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.