Evidence map›Paper›PMID 34444495›Full record

ArticleInternational journal of environmental research and public health2021

Genetic Polymorphism of Delta Aminolevulinic Acid Dehydratase (

Jamila Alessandra Perini, Mayara Calixto Silva, Ana Claudia Santiago de Vasconcellos, Paulo Victor Sousa Viana, Marcelo Oliveira Lima, Iracina Maura Jesus, Joseph William Kempton, Rogério Adas Ayres Oliveira, Sandra Souza Hacon, Paulo Cesar Basta

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Influence of theInternational journal of environmental research and public health · 2026
    Article
  2. Review
  3. Mercury Exposure and Health Effects in Indigenous People from the Brazilian Amazon-Literature-Scoping Review.International journal of environmental research and public health · 2025
    Article
  4. TheToxics · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Chronic Cadmium Exposure and Genetic Polymorphisms ofInternational journal of environmental research and public health · 2022
    Article
  10. Mercury Contamination: A Growing Threat to Riverine and Urban Communities in the Brazilian Amazon.International journal of environmental research and public health · 2022
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Jamila Alessandra PeriniLaboratório de Pesquisa de Ciências Farmacêuticas (LAPESF), Centro Universitário Estadual da Zona Oeste (UEZO), Av. Manuel Caldeira de Alvarenga, 1.203, Rio de Janeiro 23070-200, RJ, Brazil.ORCID 0000-0002-7683-0698
Mayara Calixto SilvaLaboratório de Pesquisa de Ciências Farmacêuticas (LAPESF), Centro Universitário Estadual da Zona Oeste (UEZO), Av. Manuel Caldeira de Alvarenga, 1.203, Rio de Janeiro 23070-200, RJ, Brazil.
Ana Claudia Santiago de VasconcellosLaboratório de Educação Profissional em Vigilância em Saúde, Escola Politécnica de Saúde Joaquim Venâncio, Fundação Oswaldo Cruz (EPSJV/Fiocruz), Av. Brasil, 4365-Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.
Paulo Victor Sousa VianaCentro de Referência Professor Hélio Fraga, Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz (CRPHF/ENSP/Fiocruz), Estrada de Curicica, 2000-Curicica, Rio de Janeiro 22780-195, RJ, Brazil.
Marcelo Oliveira LimaSeção de Meio Ambiente, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde (SEAMB/IEC/SVS/MS), Rodovia BR-316 km 7 s/n-Levilândia, Ananindeua 67030-000, PA, Brazil.ORCID 0000-0003-3983-1672
Iracina Maura JesusSeção de Meio Ambiente, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde (SEAMB/IEC/SVS/MS), Rodovia BR-316 km 7 s/n-Levilândia, Ananindeua 67030-000, PA, Brazil.
Joseph William KemptonFaculty of Medicine, Imperial College London, Medical School Building, St Mary's Hospital, Norfolk Place, London W2 1PG, UK.
Rogério Adas Ayres OliveiraFaculdade de Medicina, Universidade de São Paulo-USP, São Paulo 01246-903, SP, Brazil.
Sandra Souza HaconDepartamento de Endemias Samuel Pessoa, Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz (ENSP/Fiocruz), Rua Leopoldo Bulhões, 1480-Manguinhos, Rio de Janeiro 21041-210, RJ, Brazil.ORCID 0000-0002-8222-0992
Paulo Cesar BastaDepartamento de Endemias Samuel Pessoa, Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz (ENSP/Fiocruz), Rua Leopoldo Bulhões, 1480-Manguinhos, Rio de Janeiro 21041-210, RJ, Brazil.ORCID 0000-0003-0804-0413
Escola Nacional de Saúde Pública · BRMinistério da Saúde · BRUniversidade Estadual da Zona Oeste · BRFundação Oswaldo Cruz · BRSt Mary's Hospital · GBUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic polymorphisms involved in mercury toxicokinetics and toxicodynamics may be associated with severe mercury toxicity. This study aimed to investigate the impact of an

Indexed as

MercuryPorphobilinogen SynthaseAnimalsChildChild, PreschoolFemaleGene FrequencyGenotypeHumansMalePolymorphism, GeneticMercuryPorphobilinogen SynthaseALADenvironmental healthgenetic polymorphismindigenous peoplemercury exposureneurotoxicity

Identifiers

PMID34444495
PMCPMC8394242
OpenAlexW3193572862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.