Evidence map›Paper›PMID 34444383›Full record

ArticleInternational journal of environmental research and public health2021

Association of Family History and Life Habits in the Development of Colorectal Cancer: A Matched Case-Control Study in Mexico.

María Del Pilar Ramírez-Díaz, María T Alvarez-Bañuelos, Martha S Robaina-Castellanos, Pedro P Castro-Enríquez, Raúl E Guzmán-García

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Emerging trends in the global burden of colorectal cancer.Nature reviews. Clinical oncology · 2026
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

María Del Pilar Ramírez-DíazFacultad de Nutrición, Universidad del Istmo, Juchitán 70102, Oaxaca, Mexico.ORCID 0000-0003-0720-9125
María T Alvarez-BañuelosInstituto de Salud Pública, Universidad Veracruzana, Xalapa 91190, Veracruz, Mexico.ORCID 0000-0003-1922-8673
Martha S Robaina-CastellanosInstituto Nacional de Oncología y Radiobiología, La Habana 10400, Cuba.ORCID 0000-0002-5975-6190
Pedro P Castro-EnríquezInstituto de Salud Pública, Universidad Veracruzana, Xalapa 91190, Veracruz, Mexico.ORCID 0000-0003-1653-0607
Raúl E Guzmán-GarcíaCentro Estatal de Cancerología "Dr. Miguel Dorantes Mesa", Xalapa 91130, Veracruz, Mexico.ORCID 0000-0001-5838-4076
Universidad Veracruzana · MXInstituto de Oncología y Radiobiología · CU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most frequently diagnosed cancers and, as such, is important for public health. The increased incidence of this neoplasm is attributed to non-modifiable controls such as family history and modifiable variable behavioral risk factors involved in lifestyle like diets in Mexico. The presence of these factors is unknown. Therefore, the aim of this study was to evaluate family history and lifestyle factors associated with developing colorectal cancer in a Mexican population. Descriptive statistics and multivariate logistic regression were used to estimate the adjusted odds ratios (OR), as well as the 95% confidence intervals (CI). In this paper, significant differences were demonstrated between cases and controls. A family history of cancer (FHC) increased the probability of CRC [OR = 3.19 (95% CI: 1.81-5.60)]. The area of urban residence was found to be a protective factor compared to the rural area. This was also the case for frequent consumption of fruits [OR = 0.49 (95% CI: 0.28-0.88)], the frequent consumption of beef [OR = 2.95 (95% CI: 1.05-8.26)], pork [OR = 3.26 (95% CI: 1.34-7.90)], and region-typical fried food [OR = 2.79 (95% CI (1.32-5.89)]. These results provide additional evidence supporting the association of some CRC risk factors with family history of cancer, low fruit consumption, high consumption of red meat, and fried foods typical of the region of México. It is important to establish intervention methods, as well as genetic counseling to relatives of patients with CRC.

Indexed as

Colorectal NeoplasmsAnimalsCase-Control StudiesCattleDietHabitsHumansMexicoOdds RatioRisk Factorscase-controlcolorectal cancerdietaryepidemiologyfamily history

Identifiers

PMID34444383
PMCPMC8391556
OpenAlexW3194198173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.