Evidence map›Paper›PMID 34443959›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Metal-Based Nanomaterials: Work as Drugs and Carriers against Viral Infections.

Junlei Yang, Lihuan Yue, Zhu Yang, Yuqing Miao, Ruizhuo Ouyang, Yihong Hu

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Potential ofBioMed research international · 2022
    Pooled it
  2. Article
  3. Review
  4. Exploring the Inhibitory Effect of AgBiSInternational journal of molecular sciences · 2023
    Article
  5. Review
  6. Recent Advances in Antiviral Activities of Triterpenoids.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Junlei YangInstitute of Bismuth Science, University of Shanghai for Science and Technology, Shanghai 200093, China.
Lihuan YueCAS Key Laboratory of Molecular Virology & Immunology, Institutional Center for Shared Technologies and Facilities, Pathogen Discovery and Big Data Center, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Yueyang Road 320, Shanghai 200031, China.
Zhu YangInstitute of Bismuth Science, University of Shanghai for Science and Technology, Shanghai 200093, China.
Yuqing MiaoInstitute of Bismuth Science, University of Shanghai for Science and Technology, Shanghai 200093, China.
Ruizhuo OuyangInstitute of Bismuth Science, University of Shanghai for Science and Technology, Shanghai 200093, China.
Yihong HuInstitut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Yueyang Road 320, Shanghai 200031, China.ORCID 0000-0001-8539-0885

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virus infection is one of the threats to the health of organisms, and finding suitable antiviral agents is one of the main tasks of current researchers. Metal ions participate in multiple key reaction stages of organisms and maintain the important homeostasis of organisms. The application of synthetic metal-based nanomaterials as an antiviral therapy is a promising new research direction. Based on the application of synthetic metal-based nanomaterials in antiviral therapy, we summarize the research progress of metal-based nanomaterials in recent years. This review analyzes the three inhibition pathways of metal nanomaterials as antiviral therapeutic materials against viral infections, including direct inactivation, inhibition of virus adsorption and entry, and intracellular virus suppression; it further classifies and summarizes them according to their inhibition mechanisms. In addition, the use of metal nanomaterials as antiviral drug carriers and vaccine adjuvants is summarized. The analysis clarifies the antiviral mechanism of metal nanomaterials and broadens the application in the field of antiviral therapy.

Indexed as

antiviral therapyapplicationcharacteristicsmechanismmetal-based nanomaterials

Identifiers

PMID34443959
PMCPMC8400983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.